Varaico: Literature-Extracted Genetic Variants

Gene:MDM4
Variant:p.S314A
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MDM4

NM_002393.5:p.S314A

Associated Papers

FLT4 activation promotes acute lymphoid leukemia survival through stabilization of MDM2/MDMX and inactivation of p53.

Haferssas D et al.

Oncogenesis, 2025

AXL receptor signalling suppresses p53 in melanoma through stabilization of the MDMX-MDM2 complex.

de Polo A et al.

Journal of Molecular Cell Biology, 2017

Human epidermal growth factor receptor 4 (Her4) Suppresses p53 Protein via Targeting the MDMX-MDM2 Protein Complex: IMPLICATION OF A NOVEL MDMX SER-314 PHOSPHOSITE.

Gerarduzzi C et al.

The Journal of Biological Chemistry, 2016

Phosphorylation of MdmX by CDK2/Cdc2(p34) is required for nuclear export of Mdm2.

Elias B et al.

Oncogene, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."