Varaico: Literature-Extracted Genetic Variants

Gene:MDM4
Variant:p.K478R
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MDM4

NM_002393.5:p.K478R

Associated Papers

Cryptic in vitro ubiquitin ligase activity of HDMX towards p53 is probably regulated by an induced fit mechanism.

Calderon-González KG et al.

Bioscience Reports, 2022

Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.

Nomura K et al.

Nature Structural & Molecular Biology, 2017

A site-directed mutagenesis study of the MdmX RING domain.

Egorova O et al.

Biochemical and Biophysical Research Communications, 2014

Modification of MDMX by sumoylation.

Pan Y et al.

Biochemical and Biophysical Research Communications, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."