Associated Papers
Genetics of Autism Spectrum Disorder underscores the role of altered spontaneous neuronal activity as a catalyst for the neurodevelopmental anomalies.
Dey S et al.
Brain Research, 2026
The Ca2+ Bridge: From Neurons to Circuits in Rett Syndrome.
Molina Calistro L et al.
International Journal of Molecular Sciences, 2025
Exploring the complexity of MECP2 function in Rett syndrome.
Liu Y et al.
Nature Reviews. Neuroscience, 2025
Variable predicted pathogenic mechanisms for novel MECP2 variants in RTT patients.
Sharaf-Eldin WE et al.
Journal, Genetic Engineering & Biotechnology, 2022
MeCP2 heterochromatin organization is modulated by arginine methylation and serine phosphorylation.
Schmidt A et al.
Frontiers in Cell and Developmental Biology, 2022
MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation.
Wittrahm R et al.
Cells, 2021
Emerging physiological and pathological roles of MeCP2 in non-neurological systems.
Wang J et al.
Archives of Biochemistry and Biophysics, 2021
Regulation of neural differentiation, synaptic scaling and animal behavior by MeCP2 phophorylation.
Zhong X et al.
Neurobiology of Learning and Memory, 2019
Fibrogenic Activity of MECP2 Is Regulated by Phosphorylation in Hepatic Stellate Cells.
Moran-Salvador E et al.
Gastroenterology, 2019
Treating Rett syndrome: from mouse models to human therapies.
Vashi N et al.
Mammalian Genome : Official Journal of the International Mammalian Genome Society, 2019
Functional assessment of MeCP2 in Rett syndrome and cancers of breast, colon, and prostate.
Pandey S et al.
Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire, 2017
MiR-130a regulates neurite outgrowth and dendritic spine density by targeting MeCP2.
Zhang Y et al.
Protein & Cell, 2016
Apoptotic Activity of MeCP2 Is Enhanced by C-Terminal Truncating Mutations.
Williams AA et al.
Plos One, 2016
The complex genetics in autism spectrum disorders.
Hua R et al.
Science China. Life Sciences, 2015
Rett syndrome: a complex disorder with simple roots.
Lyst MJ et al.
Nature Reviews. Genetics, 2015
Role of mecp2 in experience-dependent epigenetic programming.
Zimmermann CA et al.
Genes, 2015
Rett syndrome and the urge of novel approaches to study MeCP2 functions and mechanisms of action.
Bedogni F et al.
Neuroscience and Biobehavioral Reviews, 2014
Regulation and function of stimulus-induced phosphorylation of MeCP2.
Li H et al.
Frontiers in Biology, 2014
MeCP2 suppresses nuclear microRNA processing and dendritic growth by regulating the DGCR8/Drosha complex.
Cheng TL et al.
Developmental Cell, 2014
MeCP2-Related Diseases and Animal Models.
Ezeonwuka CD et al.
Diseases (basel, Switzerland), 2014
MeCP2 post-translational modifications: a mechanism to control its involvement in synaptic plasticity and homeostasis?
Bellini E et al.
Frontiers in Cellular Neuroscience, 2014
MeCP2 phosphorylation in the brain: from transcription to behavior.
Damen D et al.
Biological Chemistry, 2013
Beyond Widespread Mecp2 Deletions to Model Rett Syndrome: Conditional Spatio-Temporal Knockout, Single-Point Mutations and Transgenic Rescue Mice.
Li W et al.
Autism-open Access, 2012
The histone H3K36 demethylase Rph1/KDM4 regulates the expression of the photoreactivation gene PHR1.
Liang CY et al.
Nucleic Acids Research, 2011
In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system.
Díaz de León-Guerrero S et al.
The European Journal of Neuroscience, 2011
Autonomic dysfunction with mutations in the gene that encodes methyl-CpG-binding protein 2: insights into Rett syndrome.
Lioy DT et al.
Autonomic Neuroscience : Basic & Clinical, 2011
Synaptic determinants of rett syndrome.
Boggio EM et al.
Frontiers in Synaptic Neuroscience, 2010
Methyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosis.
Bracaglia G et al.
Embo Reports, 2009
Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function.
Tao J et al.
Proceedings of the National Academy of Sciences of the United States of America, 2009