Associated Papers
Hsp70 incompletely disaggregates misfolded K488X-menin to promote tumourigenesis in a family with multiple endocrine neoplasia type 1.
Zeng Z et al.
Cellular Signalling, 2025
Genomic and transcriptomic landscapes of metastatic neuroendocrine neoplasms from distinct primary sites and their clinical implications.
Wee K et al.
Scientific Reports, 2025
Multi-locus inherited neoplasia alleles syndromes in cancer: implications for clinical practice.
Yuen J et al.
European Journal of Human Genetics : Ejhg, 2025
Thymic neuroendocrine tumors in patients with multiple endocrine neoplasia type 1.
Yliaska I et al.
Endocrine, 2022
Whole-exome sequencing identifies somatic mutations and intratumor heterogeneity in inflammatory breast cancer.
Luo R et al.
Npj Breast Cancer, 2021
Clinical aspects of multiple endocrine neoplasia type 1.
Al-Salameh A et al.
Nature Reviews. Endocrinology, 2021
Thymic Carcinoid as the First Manifestation of Multiple Endocrine Neoplasia Type 1 Syndrome: A Case Report and Review of the Literature.
Zheng M et al.
Annals of Clinical and Laboratory Science, 2020
Genetic testing for hereditary hyperparathyroidism and familial hypocalciuric hypercalcaemia in a large UK cohort.
Mariathasan S et al.
Clinical Endocrinology, 2020
Outcome of Clinical Genetic Testing in Patients with Features Suggestive for Hereditary Predisposition to PTH-Mediated Hypercalcemia.
Khairi S et al.
Hormones & Cancer, 2020
Novel Mutations in Serbian MEN1 Patients: Genotype-phenotype Correlation.
Isailovic T et al.
Journal of Medical Biochemistry, 2019
Germline mutation landscape of multiple endocrine neoplasia type 1 using full gene next-generation sequencing.
Carvalho RA et al.
European Journal of Endocrinology, 2018
Multiple endocrine neoplasia type 1: analysis of germline MEN1 mutations in the Italian multicenter MEN1 patient database.
Marini F et al.
Endocrine, 2018
Molecular characterization of metastatic pancreatic neuroendocrine tumors (PNETs) using whole-genome and transcriptome sequencing.
Wong HL et al.
Cold Spring Harbor Molecular Case Studies, 2018
Mutational and large deletion study of genes implicated in hereditary forms of primary hyperparathyroidism and correlation with clinical features.
Pardi E et al.
Plos One, 2017
Clinical and Genetic Analysis of Multiple Endocrine Neoplasia Type 1-Related Primary Hyperparathyroidism in Chinese.
Kong J et al.
Plos One, 2016
Ectopic Cushing syndrome associated with thymic carcinoid tumor as the first presentation of MEN1 syndrome-report of a family with MEN1 gene mutation.
Hasani-Ranjbar S et al.
Familial Cancer, 2014
Primary hyperparathyroidism in MEN1 patients: a cohort study with longterm follow-up on preferred surgical procedure and the relation with genotype.
Pieterman CR et al.
Annals of Surgery, 2012
Early-onset, progressive, frequent, extensive, and severe bone mineral and renal complications in multiple endocrine neoplasia type 1-associated primary hyperparathyroidism.
Lourenço DM et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 2010
Identification of multiple endocrine neoplasia type 1 in patients with apparent sporadic primary hyperparathyroidism.
Yip L et al.
Surgery, 2008
Clinical testing for mutations in the MEN1 gene in Sweden: a report on 200 unrelated cases.
Tham E et al.
The Journal of Clinical Endocrinology and Metabolism, 2007
Multiple endocrine neoplasia type 1 in Northern Finland; clinical features and genotype phenotype correlation.
Vierimaa O et al.
European Journal of Endocrinology, 2007
A report of a national mutation testing service for the MEN1 gene: clinical presentations and implications for mutation testing.
Cardinal JW et al.
Journal of Medical Genetics, 2005
Direct binding of DNA by tumor suppressor menin.
La P et al.
The Journal of Biological Chemistry, 2004
Functional studies of the MEN1 gene.
Chandrasekharappa SC et al.
Journal of Internal Medicine, 2003
Multiple endocrine neoplasia type 1 (MEN1) germline mutations in familial isolated primary hyperparathyroidism.
Pannett AA et al.
Clinical Endocrinology, 2003
Genetic screening for MEN1 mutations in families presenting with familial primary hyperparathyroidism.
Perrier ND et al.
World Journal of Surgery, 2002
Pituitary disease in MEN type 1 (MEN1): data from the France-Belgium MEN1 multicenter study.
Vergès B et al.
The Journal of Clinical Endocrinology and Metabolism, 2002
Molecular and genetic mechanisms of tumorigenesis in multiple endocrine neoplasia type-1.
Guo SS et al.
Molecular Endocrinology (baltimore, Md.), 2001
Tumor suppressor loss in pituitary tumors.
Alexander JM
Brain Pathology (zurich, Switzerland), 2001
The MEN1 gene and associated diseases: an update.
Tsukada T et al.
Endocrine Pathology, 2001
Expression analysis of endogenous menin, the product of the multiple endocrine neoplasia type 1 gene, in cell lines and human tissues.
Wautot V et al.
International Journal of Cancer, 2000
Multiple endocrine neoplasia type 1.
Pannett AA et al.
Endocrine-related Cancer, 1999
Alternative genetic pathways in parathyroid tumorigenesis.
Farnebo F et al.
The Journal of Clinical Endocrinology and Metabolism, 1999
Germline mutations in the multiple endocrine neoplasia type 1 gene: evidence for frequent splicing defects.
Mutch MG et al.
Human Mutation, 1999
Multiple endocrine neoplasia type 1: clinical and genetic topics.
Marx S et al.
Annals of Internal Medicine, 1998
Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disorders.
Giraud S et al.
American Journal of Human Genetics, 1998
Mutation analysis of the MEN1 gene in multiple endocrine neoplasia type 1, familial acromegaly and familial isolated hyperparathyroidism.
Teh BT et al.
The Journal of Clinical Endocrinology and Metabolism, 1998
Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene.
Guru SC et al.
Journal of Internal Medicine, 1998
Germline and somatic mutation of the gene for multiple endocrine neoplasia type 1 (MEN1).
Marx SJ et al.
Journal of Internal Medicine, 1998
Characterization of mutations in patients with multiple endocrine neoplasia type 1.
Bassett JH et al.
American Journal of Human Genetics, 1998
Mutations of the MEN1 tumor suppressor gene in pituitary tumors.
Zhuang Z et al.
Cancer Research, 1997
Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states.
Agarwal SK et al.
Human Molecular Genetics, 1997
Identification of the multiple endocrine neoplasia type 1 (MEN1) gene. The European Consortium on MEN1.
Lemmens I et al.
Human Molecular Genetics, 1997
Localization of the multiple endocrine neoplasia type I (MEN1) gene based on tumor loss of heterozygosity analysis.
Emmert-Buck MR et al.
Cancer Research, 1997
Positional cloning of the gene for multiple endocrine neoplasia-type 1.
Chandrasekharappa SC et al.
Science (new York, N.y.), 1997
Haplotype analysis defines a minimal interval for the multiple endocrine neoplasia type 1 (MEN1) gene.
Debelenko LV et al.
Cancer Research, 1997