Associated Papers
Hsp70 incompletely disaggregates misfolded K488X-menin to promote tumourigenesis in a family with multiple endocrine neoplasia type 1.
Zeng Z et al.
Cellular Signalling, 2025
Alternative splicing generates isoform diversity in MEN1.
Ramachandran A et al.
Endocrine Oncology (bristol, England), 2024
miR-3156-5p is downregulated in serum of MEN1 patients and regulates expression of MORF4L2.
Kooblall KG et al.
Endocrine-related Cancer, 2022
Multi-omics analyses of MEN1 missense mutations identify disruption of menin-MLL and menin-JunD interactions as critical requirements for molecular pathogenicity.
Dreijerink KMA et al.
Epigenetics & Chromatin, 2022
Identification of pathogenic missense mutations using protein stability predictors.
Gerasimavicius L et al.
Scientific Reports, 2020
MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair.
Fang M et al.
Molecular and Cellular Biology, 2013
Menin missense mutants encoded by the MEN1 gene that are targeted to the proteasome: restoration of expression and activity by CHIP siRNA.
Canaff L et al.
The Journal of Clinical Endocrinology and Metabolism, 2012
Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms.
Shimazu S et al.
Cancer Science, 2011
Menin promotes the Wnt signaling pathway in pancreatic endocrine cells.
Chen G et al.
Molecular Cancer Research : Mcr, 2008
Clinical testing for mutations in the MEN1 gene in Sweden: a report on 200 unrelated cases.
Tham E et al.
The Journal of Clinical Endocrinology and Metabolism, 2007
Rapid mutation screening for HRPT2 and MEN1 mutations associated with familial and sporadic primary hyperparathyroidism.
Howell VM et al.
The Journal of Molecular Diagnostics : Jmd, 2006
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain.
Obungu VH et al.
Oncogene, 2003
The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene.
Sukhodolets KE et al.
Molecular and Cellular Biology, 2003
Molecular and genetic mechanisms of tumorigenesis in multiple endocrine neoplasia type-1.
Guo SS et al.
Molecular Endocrinology (baltimore, Md.), 2001
Tumor suppressor loss in pituitary tumors.
Alexander JM
Brain Pathology (zurich, Switzerland), 2001
The MEN1 gene and associated diseases: an update.
Tsukada T et al.
Endocrine Pathology, 2001
Multiple endocrine neoplasia type 1.
Pannett AA et al.
Endocrine-related Cancer, 1999
Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription.
Agarwal SK et al.
Cell, 1999
Germline and somatic mutation of the gene for multiple endocrine neoplasia type 1 (MEN1).
Marx SJ et al.
Journal of Internal Medicine, 1998
Characterization of mutations in patients with multiple endocrine neoplasia type 1.
Bassett JH et al.
American Journal of Human Genetics, 1998
Analysis of recurrent germline mutations in the MEN1 gene encountered in apparently unrelated families.
Agarwal SK et al.
Human Mutation, 1998
Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states.
Agarwal SK et al.
Human Molecular Genetics, 1997