Associated Papers
Multiple endocrine neoplasia type 1 with neuroglycopenic symptoms with a novel heterozygous MEN1 gene mutation.
Jiang X et al.
World Journal of Surgical Oncology, 2025
Hsp70 incompletely disaggregates misfolded K488X-menin to promote tumourigenesis in a family with multiple endocrine neoplasia type 1.
Zeng Z et al.
Cellular Signalling, 2025
Alternative splicing generates isoform diversity in MEN1.
Ramachandran A et al.
Endocrine Oncology (bristol, England), 2024
Investigating the novel-binding site of RPA2 on Menin and predicting the effect of point mutation of Menin through protein-protein interactions.
Kaur G et al.
Scientific Reports, 2023
Multi-omics analyses of MEN1 missense mutations identify disruption of menin-MLL and menin-JunD interactions as critical requirements for molecular pathogenicity.
Dreijerink KMA et al.
Epigenetics & Chromatin, 2022
Investigating the Effects of Amino Acid Variations in Human Menin.
Biancaniello C et al.
Molecules (basel, Switzerland), 2022
Insulinoma in an adolescent female with weight loss: a case report and literature review on pediatric insulinomas.
Gupta P et al.
Endocrinology, Diabetes & Metabolism Case Reports, 2022
Multiple Endocrine Neoplasia Type 1: Latest Insights.
Brandi ML et al.
Endocrine Reviews, 2021
Whole genome sequencing of apparently mutation-negative MEN1 patients.
Backman S et al.
European Journal of Endocrinology, 2020
Correlation of mutant menin stability with clinical expression of multiple endocrine neoplasia type 1 and its incomplete forms.
Shimazu S et al.
Cancer Science, 2011
Crystal structure of menin reveals binding site for mixed lineage leukemia (MLL) protein.
Murai MJ et al.
The Journal of Biological Chemistry, 2011
The menin tumor suppressor protein is phosphorylated in response to DNA damage.
Francis J et al.
Plos One, 2011
Menin promotes the Wnt signaling pathway in pancreatic endocrine cells.
Chen G et al.
Molecular Cancer Research : Mcr, 2008
Menin critically links MLL proteins with LEDGF on cancer-associated target genes.
Yokoyama A et al.
Cancer Cell, 2008
Cutaneous lesions associated to multiple endocrine neoplasia syndrome type 1.
Vidal A et al.
Journal of the European Academy of Dermatology and Venereology : Jeadv, 2008
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.
Hughes CM et al.
Molecular Cell, 2004
Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain.
Obungu VH et al.
Oncogene, 2003
The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene.
Sukhodolets KE et al.
Molecular and Cellular Biology, 2003
Menin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23.
Yaguchi H et al.
The Journal of Biological Chemistry, 2002
Germline mutation profile of MEN1 in multiple endocrine neoplasia type 1: search for correlation between phenotype and the functional domains of the MEN1 protein.
Wautot V et al.
Human Mutation, 2002
Molecular and genetic mechanisms of tumorigenesis in multiple endocrine neoplasia type-1.
Guo SS et al.
Molecular Endocrinology (baltimore, Md.), 2001
Tumor suppressor loss in pituitary tumors.
Alexander JM
Brain Pathology (zurich, Switzerland), 2001
The MEN1 gene and associated diseases: an update.
Tsukada T et al.
Endocrine Pathology, 2001
Genetic disorders of calcium and phosphorus metabolism.
Root AW
Critical Reviews in Clinical Laboratory Sciences, 2000
Multiple endocrine neoplasia type 1.
Pannett AA et al.
Endocrine-related Cancer, 1999
Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription.
Agarwal SK et al.
Cell, 1999
Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states.
Agarwal SK et al.
Human Molecular Genetics, 1997