Varaico: Literature-Extracted Genetic Variants

Gene:MERTK
Variant:p.A21G
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MERTK

NM_006343.3:p.A21G

Associated Papers

Effects of point substitutions on the structure of toxic Alzheimer's β-amyloid channels: atomic force microscopy and molecular dynamics simulations.

Connelly L et al.

Biochemistry, 2012

Impact of the mutation A21G (Flemish variant) on Alzheimer's beta-amyloid dimers by molecular dynamics simulations.

Huet A et al.

Biophysical Journal, 2006

Neurotoxicity and physicochemical properties of Abeta mutant peptides from cerebral amyloid angiopathy: implication for the pathogenesis of cerebral amyloid angiopathy and Alzheimer's disease.

Murakami K et al.

The Journal of Biological Chemistry, 2003

Synthesis, aggregation, neurotoxicity, and secondary structure of various A beta 1-42 mutants of familial Alzheimer's disease at positions 21-23.

Murakami K et al.

Biochemical and Biophysical Research Communications, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."