Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.N375K
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MET

NM_000245.4:p.N375K

Associated Papers

MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation.

Guérin C et al.

Molecular Oncology, 2025

Dr. Kinase: predicting the drug-resistance hotspots of protein kinases.

Lin S et al.

Nucleic Acids Research, 2025

40308214 (PubMed )
Supplement: gkaf366_supplemental_file.zip › Supplementary_Table_S1.xlsx › Table_S1

MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation.

Guérin C et al.

Biorxiv : the Preprint Server for Biology, 2025

Recording and classifying MET receptor mutations in cancers.

Guérin C et al.

Elife, 2024

Characteristics and prognosis of rrDLBCL with TP53 mutations and a high-risk subgroup represented by the co-mutations of DDX3X-TP53.

Gao F et al.

Cancer Medicine, 2023

36971051 (PubMed )
Supplement: CAM4-12-10267-s001.xlsx › Sheet1

Novel germline MET pathogenic variants in French patients with papillary renal cell carcinomas type I.

Sebai M et al.

Human Mutation, 2022

Molecular pathogenesis of hereditary lung cancer: a literature review.

Rammal S et al.

Pharmacogenomics, 2021

Rapid Disease Progression in a Patient with Advanced NSCLC Harboring a Germline MET Exon 14 Skipping Mutation: A Case Report.

Jiao Y et al.

Oncotargets and Therapy, 2021

Mutation Spectrum of EGFR From 21,324 Chinese Patients With Non-Small Cell Lung Cancer (NSCLC) Successfully Tested by Multiple Methods in a CAP-Accredited Laboratory.

Mao L et al.

Pathology Oncology Research : Por, 2021

34257561 (PubMed )
Supplement: DataSheet1.PDF

Genetic Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma: A Systemic Review and Association Analysis With Next-Generation Sequencing.

Gao F et al.

Frontiers in Genetics, 2021

34925435 (PubMed )
Supplement: DataSheet2.xlsx › Sheet1

Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review.

Cheng YI et al.

Bmc Cancer, 2019

Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.

Su D et al.

Nature Communications, 2019

31700061 (PubMed )
Supplement: 41467_2019_12846_MOESM18_ESM.xlsx › Mutation

Impaired ligand-dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer.

Miao W et al.

Cancer Science, 2019

Comparative mutational evaluation of multiple lung cancers by multiplex oncogene mutation analysis.

Takahashi Y et al.

Cancer Science, 2018

ARID1B alterations identify aggressive tumors in neuroblastoma.

Lee SH et al.

Oncotarget, 2017

28521285 (PubMed )
Supplement: oncotarget-08-45943-s002.xlsx › SupplTable2

Exome sequencing deciphers a germline MET mutation in familial epidermal growth factor receptor-mutant lung cancer.

Tode N et al.

Cancer Science, 2017

Next-generation sequencing of tyrosine kinase inhibitor-resistant non-small-cell lung cancers in patients harboring epidermal growth factor-activating mutations.

Masago K et al.

Bmc Cancer, 2015

Germline mutations causing familial lung cancer.

Tomoshige K et al.

Journal of Human Genetics, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."