Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.P991S
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MET

NM_000245.4:p.P991S

Associated Papers

Clinical Implications of Circulating Tumor DNA in Multiple Myeloma and Its Precursor Diseases.

Park SS et al.

Annals of Laboratory Medicine, 2025

40017228 (PubMed )
Supplement: alm-45-3-279-supple2.xlsx › Table_S3

Therapeutic advances of targeting receptor tyrosine kinases in cancer.

Tomuleasa C et al.

Signal Transduction and Targeted Therapy, 2024

Recording and classifying MET receptor mutations in cancers.

Guérin C et al.

Elife, 2024

Exome sequencing of Japanese schizophrenia multiplex families supports the involvement of calcium ion channels.

Toyama M et al.

Plos One, 2022

35536790 (PubMed )
Supplement: pone.0268321.s003.xlsx › Sheet1

Clinicopathologic Characteristics of Grade 2/3 Meningiomas: A Perspective on the Role of Next-Generation Sequencing.

Kim J et al.

Frontiers in Oncology, 2022

35774130 (PubMed )
Supplement: DataSheet_2.xlsx › Sheet2

MET-dependent solid tumours - molecular diagnosis and targeted therapy.

Guo R et al.

Nature Reviews. Clinical Oncology, 2020

Therapeutic Efficacy of ABN401, a Highly Potent and Selective MET Inhibitor, Based on Diagnostic Biomarker Test in MET-Addicted Cancer.

Kim J et al.

Cancers, 2020

Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models.

Engstrom LD et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017

Exon 14 Deleted MET Receptor as a New Biomarker and Target in Cancers.

Cortot AB et al.

Journal of the National Cancer Institute, 2017

MET receptor variant R970C favors calpain-dependent generation of a fragment promoting epithelial cell scattering.

Montagne R et al.

Oncotarget, 2017

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Holehouse AS et al.

Plos One, 2015

26659599 (PubMed )
Supplement: pone.0144692.s002.xlsx › suppTable_2.txt

Detection and therapeutic implications of c-Met mutations in small cell lung cancer and neuroendocrine tumors.

Voortman J et al.

Current Pharmaceutical Design, 2013

The role of the c-Met pathway in lung cancer and the potential for targeted therapy.

Sattler M et al.

Therapeutic Advances in Medical Oncology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."