Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.Y1003C
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MET

NM_000245.4:p.Y1003C

Associated Papers

Expert consensus on the diagnosis and treatment of non-small cell lung cancer with MET alteration.

Feng H et al.

Cancer Biology & Medicine, 2025

40200811 (PubMed )
Supplement: cbm-22-237-s001.pdf

Whole-Exome Sequencing Reveals Novel Candidate Driver Mutations and Potential Druggable Mutations in Patients with High-Risk Neuroblastoma.

Nokchan N et al.

Journal of Personalized Medicine, 2024

39338204 (PubMed )
Supplement: jpm-14-00950-s001.zip › Supplementary_Table_S5.xlsx › Supplementary_Table_S5.

An Investigation of the Immune Microenvironment and Genome during Lung Adenocarcinoma Development.

Wang Q et al.

Journal of Cancer, 2024

38370388 (PubMed )
Supplement: jcav15p1687s1.zip › Supplementary_Materials › Clinical_and_Genomic_Data.xlsx › Gene_mutation

MET Signaling Pathways, Resistance Mechanisms, and Opportunities for Target Therapies.

Rivas S et al.

International Journal of Molecular Sciences, 2022

36430388 (PubMed )
Supplement: ijms-23-13898-s001.zip › ijms-1981646-supplementary.pdf

Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology.

Adib E et al.

Genome Medicine, 2022

35428358 (PubMed )
Supplement: 13073_2022_1041_MOESM2_ESM.xlsx › S4_MET_Druggable

Case Report: A 91-Year-Old Patient With Non-Small Cell Lung Cancer Harboring MET Y1003S Point Mutation.

Gao B et al.

Frontiers in Medicine, 2021

A reply to "MET-mutant cancer and immune checkpoint inhibitors: A large database analysis".

Mi J et al.

Lung Cancer (amsterdam, Netherlands), 2020

Characterization of MET exon 14 alteration and association with clinical outcomes of crizotinib in Chinese lung cancers.

Yang H et al.

Lung Cancer (amsterdam, Netherlands), 2020

MET-dependent solid tumours - molecular diagnosis and targeted therapy.

Guo R et al.

Nature Reviews. Clinical Oncology, 2020

Targeting MET Dysregulation in Cancer.

Recondo G et al.

Cancer Discovery, 2020

Frequency of MET exon 14 skipping mutations in non-small cell lung cancer according to technical approach in routine diagnosis: results from a real-life cohort of 2,369 patients.

Champagnac A et al.

Journal of Thoracic Disease, 2020

Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14-mutant Non-small Cell Lung Cancer.

Suzawa K et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."