Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.H1094L
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MET

NM_000245.4:p.H1094L

Associated Papers

Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy.

Bumpers QA et al.

Journal of Medicinal Chemistry, 2024

39088797 (PubMed )
Supplement: jm4c01232_si_001.pdf

MET-dependent solid tumours - molecular diagnosis and targeted therapy.

Guo R et al.

Nature Reviews. Clinical Oncology, 2020

Biomarker-Based Phase II Trial of Savolitinib in Patients With Advanced Papillary Renal Cell Cancer.

Choueiri TK et al.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 2017

Pulmonary Sarcomatoid Carcinomas Commonly Harbor Either Potentially Targetable Genomic Alterations or High Tumor Mutational Burden as Observed by Comprehensive Genomic Profiling.

Schrock AB et al.

Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer, 2017

Clinical Actionability of Comprehensive Genomic Profiling for Management of Rare or Refractory Cancers.

Hirshfield KM et al.

The Oncologist, 2016

The role of the c-Met pathway in lung cancer and the potential for targeted therapy.

Sattler M et al.

Therapeutic Advances in Medical Oncology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."