Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.G1119V
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MET

NM_000245.4:p.G1119V

Associated Papers

Activating Point Mutations in the MET Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors.

Pecci F et al.

Cancer Discovery, 2024

38564707 (PubMed )
Supplement: cd-23-1217_supplementary_table_5_suppst5.xlsx › table_uff

LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.

Yan SB et al.

Investigational New Drugs, 2013

The role of the c-Met pathway in lung cancer and the potential for targeted therapy.

Sattler M et al.

Therapeutic Advances in Medical Oncology, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."