Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.R1166Q
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MET

NM_000245.4:p.R1166Q

Associated Papers

Discovery of a MET -driven monogenic cause of steatotic liver disease.

Pinto E Vairo F et al.

Hepatology (baltimore, Md.), 2025

The Impact of Genetic Mutations on the Efficacy of Immunotherapies in Lung Cancer.

Lui K et al.

International Journal of Molecular Sciences, 2024

Activating Point Mutations in the MET Kinase Domain Represent a Unique Molecular Subset of Lung Cancer and Other Malignancies Targetable with MET Inhibitors.

Pecci F et al.

Cancer Discovery, 2024

38564707 (PubMed )
Supplement: cd-23-1217_supplementary_table_3_suppst3.pdf

Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain.

Estevam GO et al.

Biorxiv : the Preprint Server for Biology, 2024

Altered cytoplasmic and nuclear ADP-ribosylation levels analyzed with an improved ADP-ribose binder are a prognostic factor in renal cell carcinoma.

Schraml P et al.

The Journal of Pathology. Clinical Research, 2023

36999983 (PubMed )
Supplement: CJP2-9-273-s001.xlsx › Tumor_30

Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Sobahy TM et al.

Bmc Medical Genomics, 2022

35468810 (PubMed )
Supplement: 12920_2022_1235_MOESM3_ESM.xlsx › OncoKB_unspecified-alterations.

Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma.

Bakouny Z et al.

Nature Communications, 2021

33547292 (PubMed )
Supplement: 41467_2021_21068_MOESM4_ESM.xlsx › oncop_maf

Medullary Pancreatic Carcinoma Due to Somatic POLE Mutation: A Distinctive Pancreatic Carcinoma With Marked Long-Term Survival.

Kryklyva V et al.

Pancreas, 2020

32658072 (PubMed )
Supplement: mpa-49-999-s001.pdf

Impact of MET inhibition on small-cell lung cancer cells showing aberrant activation of the hepatocyte growth factor/MET pathway.

Taniguchi H et al.

Cancer Science, 2017

Gastrointestinal malignancies harbor actionable MET exon 14 deletions.

Lee J et al.

Oncotarget, 2015

26375439 (PubMed )
Supplement: oncotarget-06-28211-s003.xlsx › Cosmic_MET

Gene mutations in small-cell lung cancer (SCLC): results of a panel of 6 genes in a cohort of Italian patients.

Bordi P et al.

Lung Cancer (amsterdam, Netherlands), 2014

Functional analysis of HGF/MET signaling and aberrant HGF-activator expression in diffuse large B-cell lymphoma.

Tjin EP et al.

Blood, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."