Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.Y1194F
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MET

NM_000245.4:p.Y1194F

Associated Papers

Discovery of a MET -driven monogenic cause of steatotic liver disease.

Pinto E Vairo F et al.

Hepatology (baltimore, Md.), 2025

Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844).

Ugolini A et al.

Journal of Medicinal Chemistry, 2016

27355974 (PubMed )
Supplement: jm6b00280_si_001.pdf

Regulation of the wild-type and Y1235D mutant Met kinase activation.

Cristiani C et al.

Biochemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."