Varaico: Literature-Extracted Genetic Variants

Gene:MET
Variant:p.F1200L
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MET

NM_000245.4:p.F1200L

Associated Papers

Discriminating activating, deactivating and resistance variants in protein kinases.

Singh G et al.

Genome Medicine, 2025

41152984 (PubMed )
Supplement: 13073_2025_1564_MOESM2_ESM.xlsx › Table_S6

Targeting c-Met in breast cancer: From mechanisms of chemoresistance to novel therapeutic strategies.

Iweala EEJ et al.

Current Research in Pharmacology and Drug Discovery, 2024

Combination of Type I and Type II MET Tyrosine Kinase Inhibitors as Therapeutic Approach to Prevent Resistance.

Bahcall M et al.

Molecular Cancer Therapeutics, 2022

Targeting MET Dysregulation in Cancer.

Recondo G et al.

Cancer Discovery, 2020

Glesatinib Exhibits Antitumor Activity in Lung Cancer Models and Patients Harboring MET Exon 14 Mutations and Overcomes Mutation-mediated Resistance to Type I MET Inhibitors in Nonclinical Models.

Engstrom LD et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2017

A drug resistance screen using a selective MET inhibitor reveals a spectrum of mutations that partially overlap with activating mutations found in cancer patients.

Tiedt R et al.

Cancer Research, 2011

21697284 (PubMed )
Supplement: 00085472can104433-sup-f2_t4_meth.pdf
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