Associated Papers
A catalytic domain variant of mitofusin requiring a wildtype paralog for function uncouples mitochondrial outer-membrane tethering and fusion.
Engelhart EA et al.
The Journal of Biological Chemistry, 2019
Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion.
Yan L et al.
Nature Structural & Molecular Biology, 2018
Mitofusin 1 inhibits an apoptosis-associated amino-terminal conformational change in Bax, but not its mitochondrial translocation, in a GTPase-dependent manner.
Ryu SW et al.
Cancer Letters, 2012
Defective mitochondrial function and motility due to mitofusin 1 overexpression in insulin secreting cells.
Park KS et al.
The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2012
Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases.
Reddy PH et al.
Brain Research Reviews, 2011
Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1.
Park YY et al.
Journal of Cell Science, 2010
Mitochondrial dynamics in mammalian health and disease.
Liesa M et al.
Physiological Reviews, 2009
Mitofusin-1 protein is a generally expressed mediator of mitochondrial fusion in mammalian cells.
Santel A et al.
Journal of Cell Science, 2003
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