Varaico: Literature-Extracted Genetic Variants

Gene:MGMT
Variant:p.P49T
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MGMT

NM_002412.5:p.P49T

Associated Papers

KDM6B promotes PARthanatos via suppression of O6-methylguanine DNA methyltransferase repair and sustained checkpoint response.

Yang M et al.

Nucleic Acids Research, 2022

A computational model to predict the structural and functional consequences of missense mutations in O6-methylguanine DNA methyltransferase.

Thirumal Kumar D et al.

Advances in Protein Chemistry and Structural Biology, 2019

Genetic Association Between Angiotensinogen Polymorphisms and Lung Cancer Risk.

Wang H et al.

Medicine, 2015

Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding.

Daniels DS et al.

The Embo Journal, 2000

Dominant sensitization variants of human O(6)-methylguanine-DNA-methyltransferase obtained by a mutational screen of surface residues.

Brown LR et al.

Mutation Research, 2000

Specific recognition of O6-methylguanine in DNA by active site mutants of human O6-methylguanine-DNA methyltransferase.

Hazra TK et al.

Biochemistry, 1997

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."