Varaico: Literature-Extracted Genetic Variants

Gene:MIF
Variant:p.C81S
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MIF

NM_002415.2:p.C81S

Associated Papers

Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic.

Rossmueller G et al.

Molecular Cancer Therapeutics, 2023

Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch.

Schinagl A et al.

Biochemistry, 2018

Critical role of cysteine residue 81 of macrophage migration inhibitory factor (MIF) in MIF-induced inhibition of p53 activity.

Jung H et al.

The Journal of Biological Chemistry, 2008

Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif.

Burger-Kentischer A et al.

Febs Letters, 2005

Dissection of the enzymatic and immunologic functions of macrophage migration inhibitory factor. Full immunologic activity of N-terminally truncated mutants.

Kleemann R et al.

European Journal of Biochemistry, 2000

Characterization of catalytic centre mutants of macrophage migration inhibitory factor (MIF) and comparison to Cys81Ser MIF.

Kleemann R et al.

European Journal of Biochemistry, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."