Varaico: Literature-Extracted Genetic Variants

Gene:MKNK2
Variant:p.D228G
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MKNK2

NM_199054.3:p.D228G

Associated Papers

Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening.

Mishra RK et al.

Chemical Biology & Drug Design, 2019

Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.

Jauch R et al.

The Embo Journal, 2006

Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site.

Jauch R et al.

Structure (london, England : 1993), 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."