Varaico: Literature-Extracted Genetic Variants

Gene:MLH1
Variant:p.V4V
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MLH1

NM_000249.4:p.V4V

Associated Papers

Japanese Society of Medical Oncology clinical guidelines: Molecular testing for colorectal cancer treatment, 5th edition.

Bando H et al.

Cancer Science, 2024

38263580 (PubMed )
Supplement: CAS-115-1014-s001.docx

Mutation profile of non-small cell lung cancer revealed by next generation sequencing.

Chang YS et al.

Respiratory Research, 2021

Mutation status and prognostic value of KRAS and NRAS mutations in Moroccan colon cancer patients: A first report.

El Agy F et al.

Plos One, 2021

DeepCLIP: predicting the effect of mutations on protein-RNA binding with deep learning.

Grønning AGB et al.

Nucleic Acids Research, 2020

32558887 (PubMed )
Supplement: gkaa530_supplemental_files.zip › Supplementary_tables.xlsx › Table_S6

Endometrioid endometrial cancer "recurring" as high-grade serous adenocarcinoma in the inguinal lymph nodes in a patient with germline MLH1 mutated Lynch syndrome: consequence or coincidence?

Jiang W et al.

Hereditary Cancer in Clinical Practice, 2019

31139268 (PubMed )
Supplement: 13053_2019_112_MOESM1_ESM.xlsx › gxj-s1-blood

Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors.

Harada T et al.

Journal of Gastroenterology, 2018

Genetic characterisation of molecular targets in carcinoma of unknown primary.

Clynick B et al.

Journal of Translational Medicine, 2018

Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Kis O et al.

Nature Communications, 2017

28492226 (PubMed )
Supplement: ncomms15086-s1.pdf

Molecular profiling of infiltrating urothelial carcinoma of bladder and nonbladder origin.

Millis SZ et al.

Clinical Genitourinary Cancer, 2015

Microsatellite unstable gastrointestinal neuroendocrine carcinomas: a new clinicopathologic entity.

Sahnane N et al.

Endocrine-related Cancer, 2015

KRAS and BRAF Mutation Detection: Is Immunohistochemistry a Possible Alternative to Molecular Biology in Colorectal Cancer?

Piton N et al.

Gastroenterology Research and Practice, 2015

KRAS codon 12 and 13 mutations in relation to disease-free survival in BRAF-wild-type stage III colon cancers from an adjuvant chemotherapy trial (N0147 alliance).

Yoon HH et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2014

Clinical utility of KRAS and BRAF mutations in a cohort of patients with colorectal neoplasms submitted for microsatellite instability testing.

Cushman-Vokoun AM et al.

Clinical Colorectal Cancer, 2013

Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers.

Imamura Y et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2012

MSH6 and MUTYH deficiency is a frequent event in early-onset colorectal cancer.

Giráldez MD et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2010

KRAS and BRAF oncogenic mutations in MSS colorectal carcinoma progression.

Oliveira C et al.

Oncogene, 2007

Comprehensive characterization of HNPCC-related colorectal cancers reveals striking molecular features in families with no germline mismatch repair gene mutations.

Abdel-Rahman WM et al.

Oncogene, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."