Associated Papers
Multicenter In-House Evaluation of an Amplicon-Based Next-Generation Sequencing Panel for Comprehensive Molecular Profiling.
Jantus-Lewintre E et al.
Molecular Diagnosis & Therapy, 2025
Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities.
Takemon Y et al.
Genome Medicine, 2024
Evolutionary origin of germline pathogenic variants in human DNA mismatch repair genes.
Lei H et al.
Human Genomics, 2024
Outcomes and the effect of PGT-M in women with hormone-related hereditary tumor syndrome.
Wang D et al.
Frontiers in Oncology, 2024
Investigation of Clinically Significant Molecular Aberrations in Patients with Prostate Cancer: Implications for Personalized Treatment, Prognosis and Genetic Testing.
Fountzilas E et al.
International Journal of Molecular Sciences, 2023
Detection of oncogenic and clinically actionable mutations in cancer genomes critically depends on variant calling tools.
Garcia-Prieto CA et al.
Bioinformatics (oxford, England), 2022
Evaluation of yield and experiences of age-related molecular investigation for heritable and nonheritable causes of mismatch repair deficient colorectal cancer to identify Lynch syndrome.
Vos JR et al.
International Journal of Cancer, 2020
Validation Strategy for Ultrasensitive Mutation Detection.
Debeljak M et al.
Molecular Diagnosis & Therapy, 2018
Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.
Kong SL et al.
Oncotarget, 2017
Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels.
LaDuca H et al.
Plos One, 2017
Workflow optimization of whole genome amplification and targeted panel sequencing for CTC mutation detection.
Liu HE et al.
Npj Genomic Medicine, 2017
The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth.
Nivarthi H et al.
Oncotarget, 2016
Genetic profiles of cervical tumors by high-throughput sequencing for personalized medical care.
Muller E et al.
Cancer Medicine, 2015
Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.
Yurgelun MB et al.
Gastroenterology, 2015
Target enrichment using parallel nanoliter quantitative PCR amplification.
De Wilde B et al.
Bmc Genomics, 2014
Cytosine-based nucleoside analogs are selectively lethal to DNA mismatch repair-deficient tumour cells by enhancing levels of intracellular oxidative stress.
Hewish M et al.
British Journal of Cancer, 2013
ColoSeq provides comprehensive lynch and polyposis syndrome mutational analysis using massively parallel sequencing.
Pritchard CC et al.
The Journal of Molecular Diagnostics : Jmd, 2012
PhenoHM: human-mouse comparative phenome-genome server.
Sardana D et al.
Nucleic Acids Research, 2010
Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts.
Devlin LA et al.
The Ulster Medical Journal, 2008
Persistent mismatch repair deficiency following targeted correction of hMLH1.
Weiss MB et al.
Cancer Gene Therapy, 2007
Mutational targets in colorectal cancer cells with microsatellite instability.
Bertholon J et al.
Familial Cancer, 2006
Neurofibromatosis type 1 gene as a mutational target in a mismatch repair-deficient cell type.
Wang Q et al.
Human Genetics, 2003
A strategy for disease gene identification through nonsense-mediated mRNA decay inhibition.
Noensie EN et al.
Nature Biotechnology, 2001
Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae.
Shimodaira H et al.
Nature Genetics, 1998