Associated Papers
Human MutLα activates methylpurine DNA glycosylase to induce alkylation damage cytotoxicity.
Ashour ME et al.
Biorxiv : the Preprint Server for Biology, 2025
Disruption of protein-protein interaction hotspots in the C-terminal domain of MLH1 confers mismatch repair deficiency.
Fishwick KM et al.
Nar Cancer, 2025
FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.
Goold R et al.
Cell Reports, 2021
FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats.
Porro A et al.
Science Advances, 2021
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