Varaico: Literature-Extracted Genetic Variants

Gene:MLH3
Variant:p.R647C
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MLH3

NM_001040108.2:p.R647C

Associated Papers

Traditional and New Views on MSI-H/dMMR Endometrial Cancer.

Liu C et al.

Biomolecules, 2025

Genetic determinants of testicular sperm extraction outcomes: insights from a large multicentre study of men with non-obstructive azoospermia.

Riera-Escamilla A et al.

Human Reproduction Open, 2025

40896145 (PubMed )
Supplement: hoaf049_supplementary_data.zip › HRO-25-0045-R2-SuppTablesS2-S4_and_S6-S9.xlsx › ST4

Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin Lymphoma.

Gomez F et al.

Cancer Research Communications, 2023

37910143 (PubMed )
Supplement: crc-23-0140-s19.xlsx › Supplemental_Table13_Germline

Synchronous endometrial and ovarian cancer in Lynch syndrome with a MSH2 germline mutation: A case report.

Takeda T et al.

Molecular and Clinical Oncology, 2018

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

Analysis of MLH3 C2531T polymorphism in Iranian women with unexplained infertility.

Pashaiefar H et al.

Iranian Journal of Reproductive Medicine, 2013

The role of MSH5 C85T and MLH3 C2531T polymorphisms in the risk of male infertility with azoospermia or severe oligozoospermia.

Xu K et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2010

Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome.

Ou J et al.

Genes, Chromosomes & Cancer, 2009

The first functional study of MLH3 mutations found in cancer patients.

Korhonen MK et al.

Genes, Chromosomes & Cancer, 2008

MLH3 mutation in endometrial cancer.

Taylor NP et al.

Cancer Research, 2006

A role for MLH3 in hereditary nonpolyposis colorectal cancer.

Wu Y et al.

Nature Genetics, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."