Associated Papers
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization.
Meng Y et al.
Nature Communications, 2023
The MLKL kinase-like domain dimerization is an indispensable step of mammalian MLKL activation in necroptosis signaling.
Zhang Y et al.
Cell Death & Disease, 2021
Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis.
Petrie EJ et al.
Nature Communications, 2018
Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis.
Weber K et al.
Communications Biology, 2018
Structural insights into RIP3-mediated necroptotic signaling.
Xie T et al.
Cell Reports, 2013
Select a paper to view details