Varaico: Literature-Extracted Genetic Variants

Gene:MLKL
Variant:p.E351K
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MLKL

NM_152649.4:p.E351K

Associated Papers

Conformational switching of the pseudokinase domain promotes human MLKL tetramerization and cell death by necroptosis.

Petrie EJ et al.

Nature Communications, 2018

Insights into the evolution of divergent nucleotide-binding mechanisms among pseudokinases revealed by crystal structures of human and mouse MLKL.

Murphy JM et al.

The Biochemical Journal, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."