Varaico: Literature-Extracted Genetic Variants

Gene:MLKL
Variant:p.K22E
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MLKL

NM_152649.4:p.K22E

Associated Papers

Amphipathic N-terminal helices drive MLKL-mediated necroptosis through an antimicrobial peptide-like mechanism across evolution.

Tian X et al.

Developmental and Comparative Immunology, 2026

MLKL forms cation channels.

Xia B et al.

Cell Research, 2016

27033670 (PubMed )
Supplement: cr201626x5.pdf
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."