Varaico: Literature-Extracted Genetic Variants

Gene:MLLT1
Variant:p.L117_R118insNHL
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MLLT1

NM_005934.4:p.L117_R118insNHL

Associated Papers

RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription.

Budinich KA et al.

Biorxiv : the Preprint Server for Biology, 2025

Development of Chemical Tools for the Human YEATS Domain.

Guo XS et al.

Acs Chemical Biology, 2025

Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development.

Xue Z et al.

Nature Communications, 2025

Condensate-Promoting ENL Mutation Drives Tumorigenesis In Vivo Through Dynamic Regulation of Histone Modifications and Gene Expression.

Liu Y et al.

Cancer Discovery, 2024

Single-cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape.

Song L et al.

Nature Communications, 2024

Single-Cell multiomics reveals ENL mutation perturbs kidney developmental trajectory by rewiring gene regulatory landscape.

Song L et al.

Biorxiv : the Preprint Server for Biology, 2024

Conformational and Thermodynamic Differences Underlying Wild-Type and Mutant Eleven-Nineteen-Leukemia YEATS Domain Specificity for Epigenetic Marks.

Baweja L et al.

Journal of Chemical Information and Modeling, 2023

Structure and Inhibitor Binding Characterization of Oncogenic MLLT1 Mutants.

Ni X et al.

Acs Chemical Biology, 2021

MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours.

Perlman EJ et al.

Nature Communications, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."