Varaico: Literature-Extracted Genetic Variants

Gene:MMP12
Variant:p.N28D
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MMP12

NM_002426.6:p.N28D

Associated Papers

Pathogenic germline variants in small cell lung cancer: A systematic review and meta-analysis.

Ul Haq S et al.

Hgg Advances, 2025

40308030 (PubMed )
Supplement: mmc2.xlsx › Table_S3

Single Nucleotide Polymorphisms and Tendon/Ligament Injuries in Athletes: A Systematic Review and Meta-analysis.

Fukuyama Y et al.

International Journal of Sports Medicine, 2025

Association of Matrix Metalloproteinases Polymorphisms with Glaucoma Risk, Glaucoma Phenotype, and Response to Treatment with Selective Laser Trabeculoplasty or Latanoprost.

Atanasovska Velkovska M et al.

International Journal of Molecular Sciences, 2024

Association of the MMP-3, MMP-9 and MMP-12 gene polymorphisms with COPD risk: a meta-analysis.

Zhao H et al.

Archives of Medical Science : Ams, 2024

Association of GWAS-Reported Variant of Matrix Metalloproteinase 12 Gene with Susceptibility to Ischemic Stroke in Southern Chinese Population.

Chen L et al.

Journal of Inflammation Research, 2024

Genetic Variants in Matrix Metalloproteinases MMP3 (rs3025058) and MMP9 (rs3918242) Associated with Colonic Diverticulosis.

Nehring P et al.

Medicina (kaunas, Lithuania), 2023

Interleukin-1β activated c-FOS transcription factor binds preferentially to a specific allele of the matrix metalloproteinase-13 promoter and increases susceptibility to endometriosis.

Pandit A et al.

Journal of Cellular Physiology, 2022

Genetic polymorphisms associated with obesity in the Arab world: a systematic review.

Younes S et al.

International Journal of Obesity (2005), 2021

THE ROLE OF POLYMORPHISMS OF MATRIX METALLOPROTEINASES' POLYMORPHISMS 1 AND 12 IN THE FORMATION OF WHEEZING SYNDROME AMONG CHILDREN WITH RECURRENT BRONCHITIS.

Strelkova MI et al.

Wiadomosci Lekarskie (warsaw, Poland : 1960), 2021

Matrix metalloproteinases 7, 8, 12, 13 gene haplotypes associated with colorectal cancer in a Mexican population.

Moreno-Ortiz JM et al.

Gaceta Medica De Mexico, 2021

Matrix metalloproteinases as target genes for gene regulatory networks driving molecular and cellular pathways related to a multistep pathogenesis of cerebrovascular disease.

Polonikov A et al.

Journal of Cellular Biochemistry, 2019

UGT2B17 and miR-224 contribute to hormone dependency trends in adenocarcinoma and squamous cell carcinoma of esophagus.

Lian X et al.

Bioscience Reports, 2019

31164411 (PubMed )
Supplement: bsr20190472_supp1.xlsx › EA_Gene_Relation

The role of MMP-12 gene polymorphism - 82 A-to-G (rs2276109) in immunopathology of COPD in polish patients: a case control study.

Gilowska I et al.

Bmc Medical Genetics, 2019

MMP12 -82 A>G Promoter Polymorphism in Bronchial Asthma in a Population of Central Bulgaria.

Tacheva T et al.

Laboratory Medicine, 2018

Association of matrix metalloprotease 1, 3, and 12 polymorphisms with rheumatic heart disease in a Chinese Han population.

Hu W et al.

Bmc Medical Genetics, 2018

The G allele of MMP12 -82 A > G promoter polymorphism as a protective factor for COPD in Bulgarian population.

Tacheva T et al.

Archives of Physiology and Biochemistry, 2017

Gene-Gene Interactions Between Glutathione S-Transferase M1 and Matrix Metalloproteinases 1, 9, and 12 in Chronic Obstructive Pulmonary Disease in Serbians.

Stankovic M et al.

Copd, 2017

Functional single nucleotide polymorphisms of matrix metalloproteinase 7 and 12 genes in idiopathic recurrent spontaneous abortion.

Barišić A et al.

Journal of Assisted Reproduction and Genetics, 2017

Role of MMP-1 (-519A/G, -1607 1G/2G), MMP-3 (Lys45Glu), MMP-7 (-181A/G), and MMP-12 (-82A/G) Variants and Plasma MMP Levels on Obesity-Related Phenotypes and Microvascular Reactivity in a Tunisian Population.

Boumiza S et al.

Disease Markers, 2017

DiMeX: A Text Mining System for Mutation-Disease Association Extraction.

Mahmood AS et al.

Plos One, 2016

27073839 (PubMed )
Supplement: pone.0152725.s003.xlsx › Sheet1

Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1β as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients.

Markiewicz L et al.

Biomed Research International, 2015

The association between MMP-12 82 A/G polymorphism and susceptibility to various malignant tumors: a meta-analysis.

Chen SS et al.

International Journal of Clinical and Experimental Medicine, 2015

The influence of matrix metalloproteinase-2, -9, and -12 promoter polymorphisms on Iranian patients with oesophageal squamous cell carcinoma.

Eftekhary H et al.

Contemporary Oncology (poznan, Poland), 2015

Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the risk of ischemic stroke in a Tunisian population.

Chehaibi K et al.

Journal of the Neurological Sciences, 2014

Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis.

Cho MH et al.

The Lancet. Respiratory Medicine, 2014

The association of genetic variants of matrix metalloproteinases with abdominal aortic aneurysm: a systematic review and meta-analysis.

Morris DR et al.

Heart (british Cardiac Society), 2014

[Association of matrix metalloproteinases' polymorphisms of MMP3 and MMP9 with development of genital endometriosis].

Iarmolinskaia MI et al.

Genetika, 2014

Genetic determinants of chronic obstructive pulmonary disease in South Indian male smokers.

Arja C et al.

Plos One, 2014

Genetic polymorphisms in matrix metalloproteinases (MMPs) and tissue inhibitors of MPs (TIMPs), and bladder cancer susceptibility.

Wieczorek E et al.

Bju International, 2013

Gene polymorphisms of the MMP1, MMP9, MMP12, IL-1β and TIMP1 and the risk of primary open-angle glaucoma.

Markiewicz L et al.

Acta Ophthalmologica, 2013

Genetic polymorphism of matrix metalloproteinase family and chronic obstructive pulmonary disease susceptibility: a meta-analysis.

Zhou H et al.

Scientific Reports, 2013

Association of genotypes at the matrix metalloproteinase (MMP) loci with carotid IMT and presence of carotid and femoral atherosclerotic plaques.

Panayiotou AG et al.

Vascular Medicine (london, England), 2013

Gene polymorphism of matrix metalloproteinase-12 and -13 and association with colorectal cancer in Swedish patients.

VAN Nguyen S et al.

Anticancer Research, 2013

Extracellular matrix remodeling genes polymorphisms and risk of chronic bronchitis and recurrent pneumonia in children.

Korytina GF et al.

Journal of Human Genetics, 2013

Association study of matrix metalloproteinase-12 gene polymorphisms and asthma in a Japanese population.

Yamaide F et al.

International Archives of Allergy and Immunology, 2013

Single nucleotide polymorphisms in the matrix metalloproteinase gene family and the frequency and duration of gastroesophageal reflux disease influence the risk of esophageal adenocarcinoma.

Cheung WY et al.

International Journal of Cancer, 2012

Matrix metalloproteinase family gene polymorphisms and risk for coronary artery disease: systematic review and meta-analysis.

Niu W et al.

Heart (british Cardiac Society), 2012

Is MMP-7 gene polymorphism a possible risk factor for chronic obstructive pulmonary disease in Turkish patients.

Mogulkoc U et al.

Genetic Testing and Molecular Biomarkers, 2012

Polymorphisms of genes involved in extracellular matrix remodeling and abdominal aortic aneurysm.

Saracini C et al.

Journal of Vascular Surgery, 2012

Single-nucleotide polymorphisms of matrix metalloproteinases and their inhibitors in gastrointestinal cancer.

Langers AM et al.

World Journal of Gastrointestinal Oncology, 2011

Genes and abdominal aortic aneurysm.

Hinterseher I et al.

Annals of Vascular Surgery, 2011

Pharmacogenetic associations of MMP9 and MMP12 variants with cardiovascular disease in patients with hypertension.

Tanner RM et al.

Plos One, 2011

Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults.

Mukhopadhyay S et al.

The Journal of Allergy and Clinical Immunology, 2010

Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate.

van Diemen CC et al.

The European Respiratory Journal, 2010

[Association of functional polymorphisms on MMP-12 and MMP-13 gene promoter region with epithelial ovarian carcinoma].

Jia J et al.

Zhonghua Yi Xue Yi Chuan Xue Za Zhi = Zhonghua Yixue Yichuanxue Zazhi = Chinese Journal of Medical Genetics, 2010

Single nucleotide polymorphisms in matrix metalloproteinase genes and lung cancer chemotherapy response and prognosis.

Scherf DB et al.

The European Respiratory Journal, 2010

Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population.

Haq I et al.

Bmc Medical Genetics, 2010

MMP12, lung function, and COPD in high-risk populations.

Hunninghake GM et al.

The New England Journal of Medicine, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."