Varaico: Literature-Extracted Genetic Variants

Gene:MMP2
Variant:p.N245N
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MMP2

NM_004530.6:p.N245N

Associated Papers

Genotype-phenotype correlations in breast cancer susceptibility: evaluating MMP-2, TYMS, and eNOS variants in the Jordanian population.

Alorjani M et al.

Scientific Reports, 2026

Association between variants of gelatinases and lung carcinoma risk: A systematic review, meta-analysis, trial sequential analysis with prevalence and transcriptional predictions.

Shi S et al.

Medicine, 2025

Screening of single nucleotide polymorphism in matrix metalloproteinase-2 (MMP2) and tetraspanin CD63 genes in Chlamydia trachomatis-infected tubal ectopic pregnancy patients.

Pant S et al.

International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics, 2024

The Genetic Association of MMP-2 Gene Polymorphisms with the Susceptibility to Alzheimer's Disease.

Liu L et al.

Journal of Integrative Neuroscience, 2024

Association of matrix metalloproteinase-2 gene variants with diabetic nephropathy risk.

Sarray S et al.

The Journal of Gene Medicine, 2023

Analysis of MMP-2-735C/T (rs2285053) and MMP-9-1562C/T (rs3918242) Polymorphisms in the Risk Assessment of Developing Lung Cancer.

Wadowska K et al.

International Journal of Molecular Sciences, 2023

MMP2 rs243866 and rs2285053 Polymorphisms and Alzheimer's Disease Risk in Slovak Caucasian Population.

Ocenasova A et al.

Life (basel, Switzerland), 2023

Investigation of roles of IL-8 (+ 781 C/T) and MMP-2 (-735 C/T) gene variations in early diagnosis of bladder cancer and progression.

Alkanli N et al.

Molecular Biology Reports, 2023

Functionally significant polymorphisms of the MMP9 gene are associated with primary open-angle glaucoma in the population of Russia.

Ponomarenko I et al.

European Journal of Ophthalmology, 2022

Polymorphisms in Genes Involved in Inflammation and Periodontitis: A Narrative Review.

Brodzikowska A et al.

Biomolecules, 2022

Impact of MMP2 rs243849 and rs14070 genetic polymorphisms on the ischemic stroke susceptibility in Chinese Shaanxi population.

Li S et al.

Frontiers in Neurology, 2022

TT genotype of the MMP-9-1562C/T polymorphism may be a risk factor for thrombolytic therapy-induced hemorrhagic complications after acute ischemic stroke.

Dusanovic Pjevic M et al.

Pharmacotherapy, 2021

MMP-2 and MMP-9 Polymorphisms and Preeclampsia Risk in Tunisian Arabs: A Case-Control Study.

Gannoun MBA et al.

Journal of Clinical Medicine, 2021

Correlation between matrix metalloproteinase-2 polymorphisms and first and recurrent atherosclerotic ischemic stroke events: a case-control study.

Li Y et al.

The Journal of International Medical Research, 2021

Genetic Predictors of Early-Onset Spinal Intervertebral Disc Degeneration: Part One of Two.

Fiani B et al.

Cureus, 2021

Investigating the association of matrix metalloproteinase-2 gene variants with endometriosis in an Iranian population.

Tarki SE et al.

European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2021

Association of MMP2 and MMP9 gene polymorphisms with the recurrent spontaneous abortion: A meta-analysis.

Yan Y et al.

Gene, 2021

Gene variability in matrix metalloproteinases in patients with recurrent aphthous stomatitis.

Slezakova S et al.

Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2020

Matrix metalloproteinases as target genes for gene regulatory networks driving molecular and cellular pathways related to a multistep pathogenesis of cerebrovascular disease.

Polonikov A et al.

Journal of Cellular Biochemistry, 2019

Common matrix metalloproteinase-2 gene variants and altered susceptibility to breast cancer and associated features in Tunisian women.

Habel AF et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2019

Polymorphisms in MMP-14 and MMP-2 genes and ovarian cancer survival.

Vos MC et al.

Cancer Biomarkers : Section a of Disease Markers, 2019

Association analysis of genetic polymorphisms and expression levels of selected genes involved in extracellular matrix turnover and angiogenesis with the risk of age-related macular degeneration.

Oszajca K et al.

Ophthalmic Genetics, 2018

Correlations of MMP-2 and MMP-9 gene polymorphisms with the risk of hepatopulmonary syndrome in cirrhotic patients: A case-control study.

Liu JW et al.

The Kaohsiung Journal of Medical Sciences, 2018

Association between matrix metalloproteinase family gene polymorphisms and risk of ischemic stroke: A systematic review and meta-analysis of 29 studies.

Misra S et al.

Gene, 2018

Matrix metalloproteinase-2 C-735T and its interaction with matrix metalloproteinase-7 A-181G polymorphism are associated with the risk of preeclampsia: influence on total antioxidant capacity and blood pressure.

Rahimi Z et al.

Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology, 2018

Matrix metalloproteinase and tissue inhibitors of metalloproteinases gene polymorphisms in disorders that influence fertility and pregnancy complications: A systematic review and meta-analysis.

Barišić A et al.

Gene, 2018

The rs243866/243865 polymorphisms in MMP-2 gene and the relationship with BP control in obese resistant hypertensive subjects.

Ritter AMV et al.

Gene, 2018

Genetic and epigenetic variations associated with idiopathic recurrent pregnancy loss.

Arias-Sosa LA et al.

Journal of Assisted Reproduction and Genetics, 2018

Association of Maternal and Fetal Single-Nucleotide Polymorphisms in Metalloproteinase (MMP1, MMP2, MMP3, and MMP9) Genes with Preeclampsia.

Sakowicz A et al.

Disease Markers, 2018

Can Functional Polymorphisms in VEGF and MMP Predict Intraventricular Hemorrhage in Extremely Preterm Newborns?

Prasun P et al.

Developmental Neuroscience, 2018

Genetic polymorphisms and lung cancer risk: Evidence from meta-analyses and genome-wide association studies.

Liu C et al.

Lung Cancer (amsterdam, Netherlands), 2017

Gene-gene interactions in the NAMPT pathway, plasma visfatin/NAMPT levels, and antihypertensive therapy responsiveness in hypertensive disorders of pregnancy.

Luizon MR et al.

The Pharmacogenomics Journal, 2017

Relationship of long-term prognosis to MMP and TIMP polymorphisms in patients after ST elevation myocardial infarction.

Pavkova Goldbergova M et al.

Journal of Applied Genetics, 2017

Matrix metalloproteinase-2 -735C/T polymorphism is associated with resistant hypertension in a specialized outpatient clinic in Brazil.

Sabbatini AR et al.

Gene, 2017

Association between MMP2-1306 C/T polymorphism and prostate cancer susceptibility: a meta-analysis based on 3906 subjects.

Zhang K et al.

Oncotarget, 2017

MMP2, MMP9 and TIMP2 polymorphisms affect sperm parameters but not fertility in Polish males.

Kurzawski M et al.

Andrologia, 2017

MMP-2 (-1306 C/T) Polymorphism Affects Serum Matrix Metalloproteinase (MMP)-2 Levels and Correlates with Chronic Obstructive Pulmonary Disease Severity: A Case-Control Study of MMP-1 and -2 in a Tunisian Population.

Bchir S et al.

Molecular Diagnosis & Therapy, 2016

Matrix metalloproteinase-2, -9, and tissue inhibitor of MMP-2 gene polymorphisms in Taiwanese periodontitis patients.

Hsiao YF et al.

Journal of Dental Sciences, 2016

Genetic variation of MMP-2(-735 C>T) and MMP-9(-1562 C>T) gene in risk of development of HAND and severity of HAND.

Singh H et al.

The Journal of Gene Medicine, 2016

Role of metalloproteinases MMP-2 in asthma.

Toujani S et al.

La Tunisie Medicale, 2016

Associations of Matrix Metalloproteinase-9 and Tissue Inhibitory Factor-1 Polymorphisms With Parkinson Disease in Taiwan.

Chen YC et al.

Medicine, 2016

Role of MMP-2 (-1306 C/T) Polymorphism in Pituitary Adenoma.

Glebauskiene B et al.

Scientifica, 2016

Association of Common Variants in MMPs with Periodontitis Risk.

Li W et al.

Disease Markers, 2016

Genetic Alterations in Intervertebral Disc Disease.

Martirosyan NL et al.

Frontiers in Surgery, 2016

MMP1, 2, 3, 7, and 9 gene polymorphisms and urinary cancer risk: a meta-analysis.

Tao L et al.

Genetic Testing and Molecular Biomarkers, 2015

Matrix metalloproteinase-2 (MMP-2) gene polymorphism and cardiovascular comorbidity in type 2 diabetes patients.

Buraczynska M et al.

Journal of Diabetes and Its Complications, 2015

Association of matrix metalloproteinase family gene polymorphisms with lung cancer risk: logistic regression and generalized odds of published data.

Li H et al.

Scientific Reports, 2015

Matrix Metalloproteinase-2 Polymorphisms and Incident Coronary Artery Disease: A Meta-Analysis.

Shi Y et al.

Medicine, 2015

Association between matrix metalloproteinase-2 and matrix metalloproteinase-9 polymorphisms and endometriosis: A systematic review and meta-analysis.

Xin L et al.

Biomedical Reports, 2015

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