Varaico: Literature-Extracted Genetic Variants

Gene:MMP2
Variant:p.E525E
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MMP2

NM_004530.6:p.E525E

Associated Papers

A Specific Haplotype of the MMP2 Gene Promoter May Increase the Risk of Developing Cerebral Palsy.

Djuranovic Uklein A et al.

Diagnostics (basel, Switzerland), 2025

Association Between rs243866 Polymorphism of the MMP-2 Gene and Target Organ Damage in Patients with Uncontrolled Hypertension.

Giau HTN et al.

Acta Informatica Medica : Aim : Journal of the Society for Medical Informatics of Bosnia & Herzegovina : Casopis Drustva Za Medicinsku Informatiku Bih, 2025

The Association of MMP-2, MMP-9, and MMP-13 Gene Polymorphisms With Knee Osteoarthritis in the Greek Population.

Milaras C et al.

Cureus, 2024

Association of matrix metalloproteinase-2 gene variants with diabetic nephropathy risk.

Sarray S et al.

The Journal of Gene Medicine, 2023

MMP2 rs243866 and rs2285053 Polymorphisms and Alzheimer's Disease Risk in Slovak Caucasian Population.

Ocenasova A et al.

Life (basel, Switzerland), 2023

Polymorphisms in Genes Involved in Inflammation and Periodontitis: A Narrative Review.

Brodzikowska A et al.

Biomolecules, 2022

Association of Matrix Metalloproteinase-2 (MMP-2) and MMP-9 Promoter Polymorphisms, Their Serum Levels, and Activities with Coronary Artery Calcification (CAC) in an Iranian Population.

Elahirad S et al.

Cardiovascular Toxicology, 2022

Genetic variations as molecular diagnostic factors for idiopathic male infertility: current knowledge and future perspectives.

Karimian M et al.

Expert Review of Molecular Diagnostics, 2021

TT genotype of the MMP-9-1562C/T polymorphism may be a risk factor for thrombolytic therapy-induced hemorrhagic complications after acute ischemic stroke.

Dusanovic Pjevic M et al.

Pharmacotherapy, 2021

Investigating the association of matrix metalloproteinase-2 gene variants with endometriosis in an Iranian population.

Tarki SE et al.

European Journal of Obstetrics, Gynecology, and Reproductive Biology, 2021

MMP2 Polymorphism Affects Plasma Matrix Metalloproteinase (MMP)-2 Levels, and Correlates with the Decline in Lung Function in Hypersensitivity Pneumonitis Positive to Autoantibodies Patients.

Santiago-Ruiz L et al.

Biomolecules, 2019

Common matrix metalloproteinase-2 gene variants and altered susceptibility to breast cancer and associated features in Tunisian women.

Habel AF et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2019

Association between tissue inhibitor of metalloproteinase (TIMP) genetic polymorphisms and primary ovarian insufficiency (POI).

An HJ et al.

Maturitas, 2019

The rs243866/243865 polymorphisms in MMP-2 gene and the relationship with BP control in obese resistant hypertensive subjects.

Ritter AMV et al.

Gene, 2018

Gene Polymorphism of Matrix Metalloproteinase 9 in Asthenozoospermic Male Subjects.

Mohagheghi S et al.

International Journal of Fertility & Sterility, 2018

Relationship of long-term prognosis to MMP and TIMP polymorphisms in patients after ST elevation myocardial infarction.

Pavkova Goldbergova M et al.

Journal of Applied Genetics, 2017

Matrix metalloproteinase-2 -735C/T polymorphism is associated with resistant hypertension in a specialized outpatient clinic in Brazil.

Sabbatini AR et al.

Gene, 2017

Association of Common Variants in MMPs with Periodontitis Risk.

Li W et al.

Disease Markers, 2016

Matrix Metalloproteinase-2 Polymorphisms in Chronic Heart Failure: Relationship with Susceptibility and Long-Term Survival.

Beber AR et al.

Plos One, 2016

MMP-2 -1575G/A polymorphism modifies the onset of optic neuritis as a first presenting symptom in MS?

Gašparović I et al.

Journal of Neuroimmunology, 2015

Frequency of the common promoter polymorphism MMP2 -1306 C>T in a population from central Bulgaria.

Tacheva T et al.

Biotechnology, Biotechnological Equipment, 2015

Association study of five functional polymorphisms in matrix metalloproteinase-2, -3, and -9 genes with risk of primary ovarian insufficiency in Korean women.

Kim YR et al.

Maturitas, 2015

Relationship between single-nucleotide polymorphism of matrix metalloproteinase-2 gene and colorectal cancer and gastric cancer susceptibility: a meta-analysis.

Wu Z et al.

Oncotargets and Therapy, 2015

Genetic polymorphisms of matrix metalloproteinases and protein levels in chronic obstructive pulmonary disease in a Mexican population.

Hernández-Montoya J et al.

Biomarkers in Medicine, 2015

The GC + CC genotype at position -418 in TIMP-2 promoter and the -1575GA/-1306CC genotype in MMP-2 is genetic predisposing factors for prevalence of moyamoya disease.

Park YS et al.

Bmc Neurology, 2014

QRS widening rates and genetic polymorphisms of matrix metalloproteinases in a cohort of patients with chronic heart failure.

Olsen V et al.

The Canadian Journal of Cardiology, 2014

Genetic variants of matrix metalloproteinase (MMP2) gene influence metabolic syndrome susceptibility.

Yadav SS et al.

Genetic Testing and Molecular Biomarkers, 2014

Association between MMP-2 and TIMP-2 gene polymorphisms and advanced-stage endometriosis in Korean women.

Cho YJ et al.

American Journal of Reproductive Immunology (new York, N.y. : 1989), 2013

The biology of the extracellular matrix: novel insights.

Hubmacher D et al.

Current Opinion in Rheumatology, 2013

Matrix metalloproteinase-2 functional promoter polymorphism G1575A is associated with elevated circulatory MMP-2 levels and increased risk of cardiovascular disease in systemic lupus erythematosus patients.

Bahrehmand F et al.

Lupus, 2012

Polymorphisms of genes involved in extracellular matrix remodeling and abdominal aortic aneurysm.

Saracini C et al.

Journal of Vascular Surgery, 2012

Matrix metalloproteinase 13 genotype in rs640198 polymorphism is associated with severe coronary artery disease.

Vašků A et al.

Disease Markers, 2012

The matrix metalloproteinase 2-1575 gene polymorphism is associated with the risk of developing myocardial infarction in Mexican patients.

Pérez-Hernández N et al.

Journal of Atherosclerosis and Thrombosis, 2012

Analysis of MMP2 promoter polymorphisms in childhood obesity.

Morgan AR et al.

Bmc Research Notes, 2011

Single-nucleotide polymorphisms of matrix metalloproteinases and their inhibitors in gastrointestinal cancer.

Langers AM et al.

World Journal of Gastrointestinal Oncology, 2011

The role of matrix metalloproteinase-2 promoter polymorphisms in coronary artery disease and myocardial infarction.

Alp E et al.

Genetic Testing and Molecular Biomarkers, 2011

Is a single nucleotide polymorphism a risk factor for lung cancer in the matrix metalloproteinase-2 promoter?

Ayşegül B et al.

Molecular Biology Reports, 2011

Analysis of MMP2 promoter polymorphisms in patients with pseudoxanthoma elasticum.

Zarbock R et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2010

Polymorphisms in MMP-2 and MMP-9 promoter regions are associated with endometriosis.

Saare M et al.

Fertility and Sterility, 2010

Role of functional single nucleotide polymorphisms of MMP1, MMP2, and MMP9 in open angle glaucomas.

Mossböck G et al.

Molecular Vision, 2010

Association of polymorphisms of zinc metalloproteinases with clinical response to stem cell therapy.

Panovsky R et al.

Herz, 2010

Matrix metalloproteinases 2 and 3 gene polymorphisms and the risk of target vessel revascularization after percutaneous coronary intervention: Is there still room for determining genetic variation of MMPs for assessment of an increased risk of restenosis?

Verschuren JJ et al.

Disease Markers, 2010

Association of MMP1, MMP3, MMP9, and MMP12 polymorphisms with risk and clinical course of multiple sclerosis in a Polish population.

Mirowska-Guzel D et al.

Journal of Neuroimmunology, 2009

Matrix metalloproteinase-2 promoter variability in psoriasis.

Vasku V et al.

Archives of Dermatological Research, 2009

Polymorphisms of MMP-2 gene are associated with systolic heart failure prognosis.

Hua Y et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2009

Polymorphisms of MMP-2 gene are associated with systolic heart failure risk in Han Chinese.

Hua Y et al.

The American Journal of the Medical Sciences, 2009

Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis.

Benesová Y et al.

Journal of Neuroimmunology, 2008

Genetic variations and plasma levels of gelatinase A (matrix metalloproteinase-2) and gelatinase B (matrix metalloproteinase-9) in proliferative diabetic retinopathy.

Beránek M et al.

Molecular Vision, 2008

Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression.

Borghese B et al.

Human Reproduction (oxford, England), 2008

Genetic polymorphisms of matrix metalloproteinases in lung, breast and colorectal cancer.

Decock J et al.

Clinical Genetics, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."