Varaico: Literature-Extracted Genetic Variants

Gene:MORC2
Variant:p.M276I
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MORC2

NM_001303256.3:p.M276I

Associated Papers

Biological functions and molecular mechanisms of MORC2 in human diseases.

Zhao X et al.

Molecules and Cells, 2025

MORC2 phosphorylation fine tunes its DNA compaction activity.

Tan W et al.

Biorxiv : the Preprint Server for Biology, 2024

Dysregulation of splicing variants and spliceosome components in breast cancer.

Gahete MD et al.

Endocrine-related Cancer, 2022

MORC protein family-related signature within human disease and cancer.

Wang H et al.

Cell Death & Disease, 2021

Morc2a p.S87L mutant mice develop peripheral and central neuropathies associated with neuronal DNA damage and apoptosis.

Lee GS et al.

Disease Models & Mechanisms, 2021

RNF144A functions as a tumor suppressor in breast cancer through ubiquitin ligase activity-dependent regulation of stability and oncogenic functions of HSPA2.

Yang YL et al.

Cell Death and Differentiation, 2020

Roles of Splicing Factors in Hormone-Related Cancer Progression.

Takeiwa T et al.

International Journal of Molecular Sciences, 2020

Cancer-Associated MORC2-Mutant M276I Regulates an hnRNPM-Mediated CD44 Splicing Switch to Promote Invasion and Metastasis in Triple-Negative Breast Cancer.

Zhang FL et al.

Cancer Research, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."