Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.A506T
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MPL

NM_005373.3:p.A506T

Associated Papers

Non-MPL-W515K/L mutations in myeloproliferative neoplasms: Insights from two case reports and a review of the literature.

Tønne Nesse AS et al.

Expert Review of Hematology, 2025

Diagnosis- and Prognosis-Related Gene Alterations in BCR::ABL1-Negative Myeloproliferative Neoplasms.

Morishita S et al.

International Journal of Molecular Sciences, 2023

37629188 (PubMed )
Supplement: ijms-24-13008-s001.zip › ijms-2555672-supplementary.pdf

A Review of Molecular and Genetic Diagnostics of Myeloid Malignancies with Emphasis on Diagnostics in Bosnia and Herzegovina.

Kurtovic-Kozaric A et al.

Acta Medica Academica, 2021

Two activating mutations of MPL in triple-negative myeloproliferative neoplasms.

Xie J et al.

Cancer Medicine, 2019

Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.

Dallol A et al.

Journal of Translational Medicine, 2016

Molecular Pathogenesis and Clinical Significance of Driver Mutations in Primary Myelofibrosis: A Review.

Alshemmari SH et al.

Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, 2016

Molecular diagnostics of myeloproliferative neoplasms.

Langabeer SE et al.

European Journal of Haematology, 2015

Laboratory practice guidelines for detecting and reporting JAK2 and MPL mutations in myeloproliferative neoplasms: a report of the Association for Molecular Pathology.

Gong JZ et al.

The Journal of Molecular Diagnostics : Jmd, 2013

Detection of MPL mutations by a novel allele-specific PCR-based strategy.

Furtado LV et al.

The Journal of Molecular Diagnostics : Jmd, 2013

Different mutations of the human c-mpl gene indicate distinct haematopoietic diseases.

He X et al.

Journal of Hematology & Oncology, 2013

Advances in understanding the pathogenesis of familial thrombocythaemia.

Teofili L et al.

British Journal of Haematology, 2011

Thrombocytosis.

Skoda RC

Hematology. American Society of Hematology. Education Program, 2009

New mutations of MPL in primitive myelofibrosis: only the MPL W515 mutations promote a G1/S-phase transition.

Chaligné R et al.

Leukemia, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."