Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.Q516E
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MPL

NM_005373.3:p.Q516E

Associated Papers

A novel complex mutation affecting two codons in the exon 10 hotspot region of the MPL gene.

Iaquinta G et al.

Current Research in Translational Medicine, 2025

Non-MPL-W515K/L mutations in myeloproliferative neoplasms: Insights from two case reports and a review of the literature.

Tønne Nesse AS et al.

Expert Review of Hematology, 2025

Diagnosis- and Prognosis-Related Gene Alterations in BCR::ABL1-Negative Myeloproliferative Neoplasms.

Morishita S et al.

International Journal of Molecular Sciences, 2023

37629188 (PubMed )
Supplement: ijms-24-13008-s001.zip › ijms-2555672-supplementary.pdf

Thrombocytosis in children and adolescents-classification, diagnostic approach, and clinical management.

Stockklausner C et al.

Annals of Hematology, 2021

A Rare Case of Essential Thrombocythemia with Coexisting JAK2 and MPL Driver Mutations.

Jang MA et al.

Journal of Korean Medical Science, 2020

Two activating mutations of MPL in triple-negative myeloproliferative neoplasms.

Xie J et al.

Cancer Medicine, 2019

Mutation status of essential thrombocythemia and primary myelofibrosis defines clinical outcome.

Asp J et al.

Haematologica, 2016

Acquired copy-neutral loss of heterozygosity of chromosome 1p as a molecular event associated with marrow fibrosis in MPL-mutated myeloproliferative neoplasms.

Rumi E et al.

Blood, 2013

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