Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.H520P
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MPL

NM_005373.3:p.H520P

Associated Papers

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers.

Defour JP et al.

Elife, 2023

37338955 (PubMed )
Supplement: elife-81521-supp1.xlsx › plasmid_primers_DNA_sequences

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

Nie M et al.

Cell Death & Disease, 2021

33911074 (PubMed )
Supplement: 41419_2021_3695_MOESM9_ESM.xlsx › S2._Mutations_in_RC-K8
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."