Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.Y591F
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MPL

NM_005373.3:p.Y591F

Associated Papers

Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning.

Bridgford JL et al.

Blood, 2020

Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms.

Milosevic Feenstra JD et al.

Blood, 2016

Presence of atypical thrombopoietin receptor (MPL) mutations in triple-negative essential thrombocythemia patients.

Cabagnols X et al.

Blood, 2016

Phosphorylated c-Mpl tyrosine 591 regulates thrombopoietin-induced signaling.

Sangkhae V et al.

Experimental Hematology, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."