Varaico: Literature-Extracted Genetic Variants

Gene:MRAP2
Variant:p.E24*
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MRAP2

NM_138409.4:p.E24*

Associated Papers

Association of Mutations in the Melanocortin-2 Receptor Accessory Protein 2 Gene (MRAP2) and Obesity: A Systematic Review and Meta-Analysis.

Ji RL et al.

International Journal of Molecular Sciences, 2026

Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways.

Wyatt RA et al.

Human Molecular Genetics, 2025

Emerging roles of melanocortin receptor accessory proteins (MRAP and MRAP2) in physiology and pathophysiology.

Berruien NNA et al.

Gene, 2020

Decreased melanocortin-4 receptor function conferred by an infrequent variant at the human melanocortin receptor accessory protein 2 gene.

Schonnop L et al.

Obesity (silver Spring, Md.), 2016

Copy number variation (CNV) analysis and mutation analysis of the 6q14.1-6q16.3 genes SIM1 and MRAP2 in Prader Willi like patients.

Geets E et al.

Molecular Genetics and Metabolism, 2016

Melanocortin receptor accessory proteins in adrenal disease and obesity.

Jackson DS et al.

Frontiers in Neuroscience, 2015

Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.

Asai M et al.

Science (new York, N.y.), 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."