Associated Papers
Association of Mutations in the Melanocortin-2 Receptor Accessory Protein 2 Gene (MRAP2) and Obesity: A Systematic Review and Meta-Analysis.
Ji RL et al.
International Journal of Molecular Sciences, 2026
Obesity-associated MRAP2 variants impair multiple MC4R-mediated signaling pathways.
Wyatt RA et al.
Human Molecular Genetics, 2025
Emerging roles of melanocortin receptor accessory proteins (MRAP and MRAP2) in physiology and pathophysiology.
Berruien NNA et al.
Gene, 2020
Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.
Baron M et al.
Nature Medicine, 2019
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