Associated Papers
The small GTPase MRAS is a broken switch.
Bernal Astrain G et al.
Nature Communications, 2025
39809765 (PubMed )
Supplement: 41467_2025_55967_MOESM6_ESM.pdf
Natural history of MRAS-related Noonan syndrome: Evidence of mild adult-onset left ventricular hypertrophy and neuropsychiatric features.
Priolo M et al.
American Journal of Medical Genetics. Part C, Seminars in Medical Genetics, 2023
RASopathies and cardiac manifestations.
Hilal N et al.
Frontiers in Cardiovascular Medicine, 2023
The RASopathies: from pathogenetics to therapeutics.
Hebron KE et al.
Disease Models & Mechanisms, 2022
Atypical, severe hypertrophic cardiomyopathy in a newborn presenting Noonan syndrome harboring a recurrent heterozygous MRAS variant.
Pires LVL et al.
American Journal of Medical Genetics. Part A, 2021
Activating MRAS mutations cause Noonan syndrome associated with hypertrophic cardiomyopathy.
Motta M et al.
Human Molecular Genetics, 2020
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