Varaico: Literature-Extracted Genetic Variants

Gene:MRC1
Variant:p.S288C
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MRC1

NM_002438.4:p.S288C

Associated Papers

Massive contractions of myotonic dystrophy type 2-associated CCTG tetranucleotide repeats occur via double-strand break repair with distinct requirements for DNA helicases.

Papp D et al.

G3 (bethesda, Md.), 2024

Genome-wide contributions of the MutSα- and MutSβ-dependent DNA mismatch repair pathways to the maintenance of genetic stability in Saccharomyces cerevisiae.

Kadyrova LY et al.

The Journal of Biological Chemistry, 2023

The rate of spontaneous mutations in yeast deficient for MutSβ function.

Plavskin Y et al.

G3 (bethesda, Md.), 2023

Stimulation of adaptive gene amplification by origin firing under replication fork constraint.

Whale AJ et al.

Nucleic Acids Research, 2022

The Effect of Dia2 Protein Deficiency on the Cell Cycle, Cell Size, and Recruitment of Ctf4 Protein in Saccharomyces cerevisiae.

Ivanova A et al.

Molecules (basel, Switzerland), 2021

Defining the impact of mutation accumulation on replicative lifespan in yeast using cancer-associated mutator phenotypes.

Lee MB et al.

Proceedings of the National Academy of Sciences of the United States of America, 2019

Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.

Addinall SG et al.

Plos Genetics, 2011

Mrc1, Tof1 and Csm3 inhibit CAG.CTG repeat instability by at least two mechanisms.

Razidlo DF et al.

Dna Repair, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."