Varaico: Literature-Extracted Genetic Variants

Gene:MRE11
Variant:p.R572Q
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MRE11

NM_005591.4:p.R572Q

Associated Papers

Genomic Signatures from Clinical Tumor Sequencing in Patients with Breast Cancer Having Germline BRCA1/2 Mutation.

Kim JW et al.

Cancer Research and Treatment, 2023

Clinicopathological and molecular analysis of microsatellite instability in prostate cancer: a multi-institutional study in China.

Zhang H et al.

Frontiers in Oncology, 2023

Investigating the causal role of MRE11A p.E506* in breast and ovarian cancer.

Elkholi IE et al.

Scientific Reports, 2021

C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex.

Bai Y et al.

Molecular Cell, 2019

iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Wang M et al.

Scientific Reports, 2016

27527004 (PubMed )
Supplement: srep31321-s5.xls › VaribenchSelectedPure

Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Holehouse AS et al.

Plos One, 2015

26659599 (PubMed )
Supplement: pone.0144692.s002.xlsx › suppTable_2.txt

Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms.

Regal JA et al.

Human Molecular Genetics, 2013

Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia.

Mosor M et al.

Bmc Cancer, 2013

Mystery of DNA repair: the role of the MRN complex and ATM kinase in DNA damage repair.

Czornak K et al.

Journal of Applied Genetics, 2008

Alterations of the double-strand break repair gene MRE11 in cancer.

Fukuda T et al.

Cancer Research, 2001

The importance of making ends meet: mutations in genes and altered expression of proteins of the MRN complex and cancer.

Dzikiewicz-Krawczyk A

Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."