Varaico: Literature-Extracted Genetic Variants

Gene:MRE11
Variant:p.K464R
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MRE11

NM_005591.4:p.K464R

Associated Papers

Theranostic biomarkers and PARP-inhibitors effectiveness in patients with non-BRCA associated homologous recombination deficient tumors: Still looking through a dirty glass window?

Incorvaia L et al.

Cancer Treatment Reviews, 2023

MRE11:p.K464R mutation mediates olaparib resistance by enhancing DNA damage repair in HGSOC.

Zhuang X et al.

Cell & Bioscience, 2023

Mutation profiles in circulating cell-free DNA predict acquired resistance to olaparib in high-grade serous ovarian carcinoma.

Hu D et al.

Cancer Science, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."