Varaico: Literature-Extracted Genetic Variants

Gene:MRGPRX2
Variant:p.N16H
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MRGPRX2

NM_054030.4:p.N16H

Associated Papers

Mutations of MRGPRX2, drug sensitivity, and genetic markers related to disease.

Ratnayake SH et al.

The Journal of Allergy and Clinical Immunology. Global, 2025

MRGPRX2 gain-of-function mutation drives enhanced mast cell reactivity in chronic spontaneous urticaria.

Ye D et al.

The Journal of Allergy and Clinical Immunology, 2025

The structure, function, and pharmacology of MRGPRs.

Cao C et al.

Trends in Pharmacological Sciences, 2023

Naturally Occurring Missense MRGPRX2 Variants Display Loss of Function Phenotype for Mast Cell Degranulation in Response to Substance P, Hemokinin-1, Human β-Defensin-3, and Icatibant.

Alkanfari I et al.

Journal of Immunology (baltimore, Md. : 1950), 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."