Varaico: Literature-Extracted Genetic Variants

Gene:MS4A2
Variant:p.E237G
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MS4A2

NM_000139.5:p.E237G

Associated Papers

Molecular Determinants of the Human Retinal Pigment Epithelium Cell Fate and Potential Pharmacogenomic Targets for Precision Medicine.

Zibetti C

International Journal of Molecular Sciences, 2025

40565279 (PubMed )
Supplement: ijms-26-05817-s001.zip › Table_S1_NGS_qc_and_WES_April2025_2_.xlsx › D2_hiPSCsvsPBMC_SNPs_InDels

Genetic and serum biomarkers of NSAID hypersensitivity reactions.

Amo G et al.

Frontiers in Pharmacology, 2025

Evaluation value and mechanism of ADRB2 and FCER1B gene polymorphisms in preterm infants with congenital respiratory diseases.

Liu J et al.

Cellular and Molecular Biology (noisy-le-grand, France), 2023

Gene-gene and gene-environment interactions on cord blood total IgE in Chinese Han children.

Hua L et al.

Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology, 2021

Comprehensive multi-omics analysis of G6PC3 deficiency-related congenital neutropenia with inflammatory bowel disease.

Dasouki M et al.

Iscience, 2021

Association of a four-gene model with allergic diseases: Two-year follow-up of a birth cohort study.

Hua L et al.

Immunity, Inflammation and Disease, 2021

Exome-Wide Search for Genes Associated With Central Nervous System Inflammatory Demyelinating Diseases Following CHIKV Infection: The Tip of the Iceberg.

Alves-Leon SV et al.

Frontiers in Genetics, 2021

33815474 (PubMed )
Supplement: Table_2.XLSX › Table_XX

Whole-Exome Sequencing Characterized the Landscape of Somatic Mutations and Pathways in Colorectal Cancer Liver Metastasis.

Feng L et al.

Journal of Oncology, 2019

31814826 (PubMed )
Supplement: 2684075.f1.zip › 2684075.f1 › Supplemental_Table_2.xlsx › Sheet1

MS4A2-rs573790 Is Associated With Aspirin-Exacerbated Respiratory Disease: Replicative Study Using a Candidate Gene Strategy.

Pavón-Romero GF et al.

Frontiers in Genetics, 2018

Genetic variants associated with drugs-induced immediate hypersensitivity reactions: a PRISMA-compliant systematic review.

Oussalah A et al.

Allergy, 2016

A Nonsynonymous FCER1B SNP is Associated with Risk of Developing Allergic Rhinitis and with IgE Levels.

Amo G et al.

Scientific Reports, 2016

Microarray and whole-exome sequencing analysis of familial Behçet's disease patients.

Okuzaki D et al.

Scientific Reports, 2016

26785681 (PubMed )
Supplement: srep19456-s1.pdf

Identification of IL13 C1923T as a Single Nucleotide Polymorphism for Asthma in Children from Mauritius.

Ramphul K et al.

Pediatric Allergy, Immunology, and Pulmonology, 2015

Multifactor-dimensionality reduction reveals interaction of important gene variants involved in allergy.

de Guia RM et al.

International Journal of Immunogenetics, 2015

Association of the MS4A2 gene promoter C-109T or the 7th exon E237G polymorphisms with asthma risk: a meta-analysis.

Yang HJ et al.

Clinical Biochemistry, 2014

TBX1 mutation identified by exome sequencing in a Japanese family with 22q11.2 deletion syndrome-like craniofacial features and hypocalcemia.

Ogata T et al.

Plos One, 2014

24637876 (PubMed )
Supplement: pone.0091598.s004.pdf

[Study of genetic susceptibility in 198 children with asthma].

Zheng BQ et al.

Zhongguo Dang Dai Er Ke Za Zhi = Chinese Journal of Contemporary Pediatrics, 2012

FCεRI gene promoter polymorphisms and total IgE levels in susceptibility to atopic dermatitis in Korea.

Park KY et al.

Journal of Korean Medical Science, 2011

Recent human evolution has shaped geographical differences in susceptibility to disease.

Marigorta UM et al.

Bmc Genomics, 2011

21261943 (PubMed )
Supplement: 1471-2164-12-55-S8.XLS › Hoja1

Genetic and ethnic risk factors associated with drug hypersensitivity.

Kim SH et al.

Current Opinion in Allergy and Clinical Immunology, 2010

Association Between Serum IgE Levels and the CTLA4 +49A/G and FCER1B -654C/T Polymorphisms in Korean Children With Asthma.

Oh KY et al.

Allergy, Asthma & Immunology Research, 2010

Genetic profiling of human cell lines used as in vitro model to study cardiovascular pathophysiology and pharmacotoxicology.

Jeannesson E et al.

Cell Biology and Toxicology, 2009

Involvement of Fc(epsilon)R1beta gene polymorphisms in susceptibility to atopy in Korean children with asthma.

Kim ES et al.

European Journal of Pediatrics, 2009

Opposite gene by environment interactions in Karelia for CD14 and CC16 single nucleotide polymorphisms and allergy.

Zhang G et al.

Allergy, 2009

An association study of 13 SNPs from seven candidate genes with pediatric asthma and a preliminary study for genetic testing by multiple variants in Taiwanese population.

Wang JY et al.

Journal of Clinical Immunology, 2009

Genetic variability of the high-affinity IgE receptor alpha-subunit (FcepsilonRIalpha).

Potaczek DP et al.

Immunologic Research, 2009

Promoter polymorphism in the MS4A2 gene and asthma in the Indian population.

Sharma S et al.

International Archives of Allergy and Immunology, 2009

Association of three sets of high-affinity IgE receptor (FcepsilonR1) polymorphisms with aspirin-intolerant asthma.

Palikhe NS et al.

Respiratory Medicine, 2008

Identification of novel single nucleotide polymorphisms in inflammatory genes as risk factors associated with trachomatous trichiasis.

Atik B et al.

Plos One, 2008

Genetic variability of the high-affinity IgE receptor alpha subunit (Fc epsilon RI alpha) is related to total serum IgE levels in allergic subjects.

Sanak M et al.

Allergology International : Official Journal of the Japanese Society of Allergology, 2007

Additive association between FCER1A and FCER1B genetic polymorphisms and total serum IgE levels.

Potaczek DP et al.

Allergy, 2007

Multilocus analysis of atopy in Korean children using multifactor-dimensionality reduction.

Park HW et al.

Thorax, 2007

Complex gene-gene interactions in multiple sclerosis: a multifactorial approach reveals associations with inflammatory genes.

Motsinger AA et al.

Neurogenetics, 2007

A polymorphism of MS4A2 (- 109T > C) encoding the beta-chain of the high-affinity immunoglobulin E receptor (FcepsilonR1beta) is associated with a susceptibility to aspirin-intolerant asthma.

Kim SH et al.

Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology, 2006

Multifactor dimensionality reduction reveals gene-gene interactions associated with multiple sclerosis susceptibility in African Americans.

Brassat D et al.

Genes and Immunity, 2006

Multi-locus candidate gene polymorphisms and risk of myocardial infarction: a population-based, prospective genetic analysis.

Zee RY et al.

Journal of Thrombosis and Haemostasis : Jth, 2006

Lack of association between the IL13 variant Arg110Gln and susceptibility to cedar pollinosis in a Japanese population.

Cheng L et al.

International Archives of Allergy and Immunology, 2006

A comprehensive candidate gene study on bronchial asthma and juvenile idiopathic arthritis.

Schubert K et al.

Disease Markers, 2006

Polymorphisms of high-affinity IgE receptor and histamine-related genes in patients with ASA-induced urticaria/angioedema.

Choi JH et al.

Journal of Korean Medical Science, 2005

Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosis.

Barcellos LF et al.

Annals of Neurology, 2004

Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy.

Hoffjan S et al.

The Journal of Allergy and Clinical Immunology, 2004

LD mapping of maternally and non-maternally derived alleles and atopy in FcepsilonRI-beta.

Traherne JA et al.

Human Molecular Genetics, 2003

Atopic eczema/dermatitis syndrome - a genetically complex disease. New advances in discovering the genetic contribution.

Klüken H et al.

Allergy, 2003

Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease.

Zee RY et al.

The Pharmacogenomics Journal, 2002

A common FCER1B gene promoter polymorphism influences total serum IgE levels in a Japanese population.

Hizawa N et al.

American Journal of Respiratory and Critical Care Medicine, 2000

Association of the FcepsilonRIbeta gene with bronchial hyper-responsiveness in an Italian population.

Trabetti E et al.

Journal of Medical Genetics, 1998

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