Varaico: Literature-Extracted Genetic Variants

Gene:MSH2
Variant:p.Q4Q
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MSH2

NM_000251.3:p.Q4Q

Associated Papers

Japanese Society of Medical Oncology clinical guidelines: Molecular testing for colorectal cancer treatment, 5th edition.

Bando H et al.

Cancer Science, 2024

38263580 (PubMed )
Supplement: CAS-115-1014-s001.docx

The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification.

Yang Y et al.

Bmc Cancer, 2022

Mutation status and prognostic value of KRAS and NRAS mutations in Moroccan colon cancer patients: A first report.

El Agy F et al.

Plos One, 2021

Three molecular pathways model colorectal carcinogenesis in Lynch syndrome.

Ahadova A et al.

International Journal of Cancer, 2018

Molecular status of PI3KCA, KRAS and BRAF in ovarian clear cell carcinoma: an analysis of 63 patients.

Zannoni GF et al.

Journal of Clinical Pathology, 2016

Intronic and promoter polymorphisms of hMLH1/hMSH2 and colorectal cancer risk in Heilongjiang Province of China.

Li G et al.

Journal of Cancer Research and Clinical Oncology, 2015

Gly322Asp and Asn127Ser single nucleotide polymorphisms (SNPs) of hMSH2 mismatch repair gene and the risk of triple-negative breast cancer in Polish women.

Smolarz B et al.

Familial Cancer, 2015

Microsatellite unstable gastrointestinal neuroendocrine carcinomas: a new clinicopathologic entity.

Sahnane N et al.

Endocrine-related Cancer, 2015

KRAS codon 12 and 13 mutations in relation to disease-free survival in BRAF-wild-type stage III colon cancers from an adjuvant chemotherapy trial (N0147 alliance).

Yoon HH et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2014

Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.

Wang J et al.

Plos One, 2014

25372392 (PubMed )
Supplement: pone.0111694.s006.pdf

Clinical utility of KRAS and BRAF mutations in a cohort of patients with colorectal neoplasms submitted for microsatellite instability testing.

Cushman-Vokoun AM et al.

Clinical Colorectal Cancer, 2013

Aberrant splicing caused by a MLH1 splice donor site mutation found in a young Japanese patient with Lynch syndrome.

Takahashi M et al.

Familial Cancer, 2012

Screening for germline mutations of MLH1, MSH2, MSH6 and PMS2 genes in Slovenian colorectal cancer patients: implications for a population specific detection strategy of Lynch syndrome.

Berginc G et al.

Familial Cancer, 2009

Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.

Naruse H et al.

Familial Cancer, 2009

Differential cancer predisposition in Lynch syndrome: insights from molecular analysis of brain and urinary tract tumors.

Gylling AH et al.

Carcinogenesis, 2008

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."