Varaico: Literature-Extracted Genetic Variants

Gene:MSH2
Variant:p.D140insFs
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MSH2

NM_000251.3:p.D140insFs

Associated Papers

MSH2 in colorectal cancer: A comprehensive review of molecular mechanisms, clinical prognosis, and a precision oncology framework.

Zhao Y et al.

Critical Reviews in Oncology/hematology, 2026

Evolutionary origin of germline pathogenic variants in human DNA mismatch repair genes.

Lei H et al.

Human Genomics, 2024

38287404 (PubMed )
Supplement: 40246_2024_573_MOESM3_ESM.xls › MSH2

Phase separation as a possible mechanism for dosage sensitivity.

Yang L et al.

Genome Biology, 2024

38225666 (PubMed )
Supplement: 13059_2023_3128_MOESM3_ESM.xlsx › NMD_mutations

Characterization of sebaceous and non-sebaceous cutaneous manifestations in patients with lynch syndrome: a systematic review.

Aziz S et al.

Familial Cancer, 2023

36418753 (PubMed )
Supplement: 10689_2022_319_MOESM2_ESM.xlsx › Sup._2_Pathogenic_Variants

A Hereditable Mutation of MSH2 Gene Associated with Lynch Syndrome in a Five Generation Chinese Family.

Shao WH et al.

Cancer Management and Research, 2020

Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes.

DeRycke MS et al.

Molecular Genetics & Genomic Medicine, 2017

28944238 (PubMed )
Supplement: MGG3-5-553-s002.xlsx › ST1

Upper tract urothelial carcinomas: frequency of association with mismatch repair protein loss and lynch syndrome.

Harper HL et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."