Varaico: Literature-Extracted Genetic Variants

Gene:MSH2
Variant:p.K675R
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MSH2

NM_000251.3:p.K675R

Associated Papers

New insights into the mechanism of DNA mismatch repair.

Reyes GX et al.

Chromosoma, 2015

Low-grade serous carcinomas of the ovary contain very few point mutations.

Jones S et al.

The Journal of Pathology, 2012

Functional analysis of HNPCC-related missense mutations in MSH2.

Lützen A et al.

Mutation Research, 2008

Mutation in the magnesium binding site of hMSH6 disables the hMutSalpha sliding clamp from translocating along DNA.

Iaccarino I et al.

The Journal of Biological Chemistry, 2000

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha.

Iaccarino I et al.

The Embo Journal, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."