Varaico: Literature-Extracted Genetic Variants

Gene:MSH6
Variant:p.Q485*
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MSH6

NM_000179.3:p.Q485*

Associated Papers

Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients.

Crisafulli G et al.

Cancer Discovery, 2022

35522273 (PubMed )
Supplement: cd-21-1434_supplementary_figures_and_tables_suppsf1-sf7st1-st3.pdf

Longitudinal analysis of treatment-induced genomic alterations in gliomas.

Erson-Omay EZ et al.

Genome Medicine, 2017

28153049 (PubMed )
Supplement: 13073_2017_401_MOESM3_ESM.xlsx › AllMutations_Clonality

Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment.

Cahill DP et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2007

A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy.

Hunter C et al.

Cancer Research, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."