Varaico: Literature-Extracted Genetic Variants

Gene:MSH6
Variant:p.K1140R
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MSH6

NM_000179.3:p.K1140R

Associated Papers

Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair.

Barroso-González J et al.

Cell Reports, 2021

New insights into the mechanism of DNA mismatch repair.

Reyes GX et al.

Chromosoma, 2015

Dominant Saccharomyces cerevisiae msh6 mutations cause increased mispair binding and decreased dissociation from mispairs by Msh2-Msh6 in the presence of ATP.

Hess MT et al.

The Journal of Biological Chemistry, 2002

Mutation in the magnesium binding site of hMSH6 disables the hMutSalpha sliding clamp from translocating along DNA.

Iaccarino I et al.

The Journal of Biological Chemistry, 2000

hMSH2 and hMSH6 play distinct roles in mismatch binding and contribute differently to the ATPase activity of hMutSalpha.

Iaccarino I et al.

The Embo Journal, 1998

Structural, molecular and cellular functions of MSH2 and MSH6 during DNA mismatch repair, damage signaling and other noncanonical activities.

Edelbrock MA et al.

Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."