Associated Papers
The crystal structure of a constitutively active mutant RON kinase suggests an intramolecular autophosphorylation hypothesis.
Wang J et al.
Biochemistry, 2010
Significance of the entire C-terminus in biological activities mediated by the RON receptor tyrosine kinase and its oncogenic variant RON160.
Lu Y et al.
Journal of Experimental & Clinical Cancer Research : Cr, 2008
Multiple variants of the RON receptor tyrosine kinase: biochemical properties, tumorigenic activities, and potential drug targets.
Lu Y et al.
Cancer Letters, 2007
Oncogenesis of RON receptor tyrosine kinase: a molecular target for malignant epithelial cancers.
Wang MH et al.
Acta Pharmacologica Sinica, 2006
Altered exon usage in the juxtamembrane domain of mouse and human RON regulates receptor activity and signaling specificity.
Wei X et al.
The Journal of Biological Chemistry, 2005
Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential.
Zhou YQ et al.
Oncogene, 2003
The Ron oncogenic activity induced by the MEN2B-like substitution overcomes the requirement for the multifunctional docking site.
Santoro MM et al.
Oncogene, 2000
Gene structure of the human receptor tyrosine kinase RON and mutation analysis in lung cancer samples.
Angeloni D et al.
Genes, Chromosomes & Cancer, 2000
MET(PRC) mutations in the Ron receptor result in upregulation of tyrosine kinase activity and acquisition of oncogenic potential.
Williams TA et al.
Journal of Cellular Physiology, 1999
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