Varaico: Literature-Extracted Genetic Variants

Gene:MTHFR
Variant:p.E433G
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MTHFR

NM_005957.5:p.E433G

Associated Papers

The association between methionine synthase reductase c.66A>G variant and the risk of recurrent pregnancy loss: A systematic review and meta-analysis.

Zhou J et al.

Journal of Gynecology Obstetrics and Human Reproduction, 2024

Investigating the Matrix of Factor V Leiden (G1691A), Factor II Prothrombin (G2021A), MTHFR C677T and A1298G Polymorphisms in Greek Population: A Preliminary Study.

Spanoudaki M et al.

Medical Sciences (basel, Switzerland), 2024

Skin disorders in women with poor obstetric history: MTHFR polymorphisms and importance of preconceptional counseling.

Cagan M et al.

Current Medical Research and Opinion, 2024

Association of single nucleotide polymorphisms (4G/5G) of plasminogen activator inhibitor-1 and the risk factors for placenta-related obstetric complications.

Donmez HG et al.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 2023

MTHFR C677T and A1298C Polymorphisms in Breast Cancer, Gliomas and Gastric Cancer: A Review.

Petrone I et al.

Genes, 2021

Genetic polymorphisms in early-onset myocardial infarction in a sample of Iraqi patients: a pilot study.

Mohammad AM et al.

Bmc Research Notes, 2020

Genetic and environmental factors associated with homocysteine concentrations in a population of healthy young adults. Analysis of the MAGNETIC study.

Osadnik T et al.

Nutrition, Metabolism, and Cardiovascular Diseases : Nmcd, 2020

The effects of genomic polymorphisms in one-carbon metabolism pathways on survival of gastric cancer patients received fluorouracil-based adjuvant therapy.

Zhao T et al.

Scientific Reports, 2016

Effects of MTHFR genetic polymorphisms on toxicity and clinical response of irinotecan-based chemotherapy in patients with colorectal cancer.

Li P et al.

Genetic Testing and Molecular Biomarkers, 2014

Pharmacogenetics of methotrexate in acute lymphoblastic leukaemia: why still at the bench level?

Kodidela S et al.

European Journal of Clinical Pharmacology, 2014

Pharmacogenetic polymorphisms contributing to toxicity induced by methotrexate in the southern Spanish population with rheumatoid arthritis.

Plaza-Plaza JC et al.

Omics : a Journal of Integrative Biology, 2012

Methotrexate consolidation treatment according to pharmacogenetics of MTHFR ameliorates event-free survival in childhood acute lymphoblastic leukaemia.

Salazar J et al.

The Pharmacogenomics Journal, 2012

Association of the C677T polymorphism in the human methylenetetrahydrofolate reductase (MTHFR) gene with the genetic predisposition for type 2 diabetes mellitus in a Moroccan population.

Benrahma H et al.

Genetic Testing and Molecular Biomarkers, 2012

Influence of Methylenetetrahydrofolate Reductase C677T, A1298C, and G80A Polymorphisms on the Survival of Pediatric Patients with Acute Lymphoblastic Leukemia.

de Deus DM et al.

Leukemia Research and Treatment, 2012

Genetic susceptibility of methylenetetrahydrofolate reductase (MTHFR) gene C677T, A1298C, and G1793A polymorphisms with risk for bladder transitional cell carcinoma in men.

Safarinejad MR et al.

Medical Oncology (northwood, London, England), 2011

Association of MTHFR, MTR, MTRR, RFC1, and DHFR gene polymorphisms with susceptibility to sporadic colon cancer.

Jokić M et al.

Dna and Cell Biology, 2011

Investigation of inter-individual variability of the one-carbon folate pathway: a bioinformatic and genetic review.

Carr DF et al.

The Pharmacogenomics Journal, 2009

Association of folate-pathway gene polymorphisms with the risk of prostate cancer: a population-based nested case-control study, systematic review, and meta-analysis.

Collin SM et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2009

Vascular and connective tissue features in 5 Italian patients with homocystinuria.

Evangelisti L et al.

International Journal of Cardiology, 2009

A common gene variant in methionine synthase reductase is not associated with peak homocysteine concentrations after nitrous oxide anesthesia.

Nagele P et al.

Pharmacogenetics and Genomics, 2009

Evaluation of potential modifiers of the cardiac phenotype in the 22q11.2 deletion syndrome.

Goldmuntz E et al.

Birth Defects Research. Part A, Clinical and Molecular Teratology, 2009

MTHFR polymorphisms' influence on outcome and toxicity in acute lymphoblastic leukemia patients.

Chiusolo P et al.

Leukemia Research, 2007

Pharmacogenetics of acute lymphoblastic leukemia treatment response.

Cunningham L et al.

Expert Opinion on Pharmacotherapy, 2007

Prevalence of methylenetetrahydrofolate reductase polymorphisms in young patients with inflammatory bowel disease.

Stocco G et al.

Digestive Diseases and Sciences, 2006

Molecular genetic testing of polymorphisms associated with venous thrombosis: a review of molecular technologies.

Xu B et al.

Diagnostic Molecular Pathology : the American Journal of Surgical Pathology, Part B, 2005

No evidence of association of methylenetetrahydrofolate reductase polymorphism with occurrence of second neoplasms after treatment of childhood leukemia.

Jazbec J et al.

Leukemia & Lymphoma, 2005

Methylenetetrahydrofolate reductase polymorphisms and therapy response in pediatric acute lymphoblastic leukemia.

Aplenc R et al.

Cancer Research, 2005

Genetic polymorphisms of CYP1A1, CYP2D6, GSTM1, and GSTT1 and susceptibility to acute lymphoblastic leukemia in Indian children.

Aplenc R

Pediatric Blood & Cancer, 2004

Patterns of co-occurrence of three single nucleotide polymorphisms of the 5,10-methylenetetrahydrofolate reductase gene in kidney transplant recipients.

Winkelmayer WC et al.

European Journal of Clinical Investigation, 2004

Methylenetetrahydrofolate reductase genotypes do not play a role in acute lymphoblastic leukemia pathogenesis in the Italian population.

Chiusolo P et al.

Haematologica, 2004

Methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) gene polymorphisms as risk factors for hepatocellular carcinoma in a Korean population.

Kwak SY et al.

Anticancer Research, 0

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